87917

Tetramethylrhodamin-Ethylester-Perchlorat

suitable for fluorescence, ≥90% (HPCE)

• Synonym(e): TMRE
• Empirische Formel (Hill-System): C₂₆H₂₇ClN₂O₇
• CAS-Nummer: 115532-52-0
• Molekulargewicht: 514.95
• MDL-Nummer: MFCD00467973
• UNSPSC-Code: 12352116
• PubChem Substanz-ID: 329769616
• NACRES: NA.32

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥90% (HPCE)
• Form: solid
• Löslichkeit: DMSO: soluble; alcohols: soluble
• Fluoreszenz: λ_ex 540 nm; λ_em 595 nm in DMSO
• Eignung: suitable for fluorescence
• Lagertemp.: 2-8°C
• SMILES String: [O-]Cl(=O)(=O)=O.CCOC(=O)c1ccccc1-c2c3ccc(cc3[o+]c4cc(ccc24)N(C)C)N(C)C
• InChI: 1S/C26H27N2O3.ClHO4/c1-6-30-26(29)20-10-8-7-9-19(20)25-21-13-11-17(27(2)3)15-23(21)31-24-16-18(28(4)5)12-14-22(24)25;2-1(3,4)5/h7-16H,6H2,1-5H3;(H,2,3,4,5)/q+1;/p-1
• InChIKey: NBAOBNBFGNQAEJ-UHFFFAOYSA-M

Beschreibung

Allgemeine Beschreibung

Tetramethylrhodamine ethyl ester perchlorate (TMRE), also known as TMRE perchlorate, is a potential mitochondrial dye. TMRE staining process is reversible, and it doesn’t affect cell proliferation and viability.

The sorted cells containing TMRE perchlorate don’t interfere with the subsequent functional assays and hence are a preferred choice for the enrichment of functionally active, unbiased cell populations.

Anwendung

Tetramethylrhodamine ethyl ester perchlorate (TMRE) is used to study the effects of high glucose in inducing mitochondrial morphology and metabolic changes.

TMRE perchlorate is also used to study Fullerene C 60 penetration into Leukemic Cells and the subsequent photoinduced Cytotoxic Effects.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Sonstige Hinweise

Potential-sensitive probe for measuring membrane potential changes in mitochondria

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302 + H332,H315,H319
• P-Sätze: P261 - P264 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves