26740

Cholesterin

from lanolin, ≥95.0% (GC)

• Synonym(e): 3β-Hydroxy-5-cholesten, 5-Cholesten-3β-ol
• Empirische Formel (Hill-System): C₂₇H₄₆O
• CAS-Nummer: 57-88-5
• Molekulargewicht: 386.65
• Beilstein: 1915888
• EG-Nummer: 200-353-2
• MDL-Nummer: MFCD00003646
• UNSPSC-Code: 12352200
• eCl@ss: 39023139
• PubChem Substanz-ID: 57648186

Eigenschaften

• Biologische Quelle: lanolin
• Assay: ≥95.0% (GC)
• Form: powder with small lumps
• Optische Aktivität: [α]20/D −36±2°, c = 2% in dioxane
• bp: 360 °C (lit.)
• mp (Schmelzpunkt): 147-149 °C (lit.); 147-150 °C
• Dichte: 1.067 g/mL at 25 °C (lit.)
• Lagertemp.: 2-8°C
• SMILES String: CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
• InChIKey: HVYWMOMLDIMFJA-DPAQBDIFSA-N
• Angaben zum Gen: human ... POLA1(5422) , TOP2A(7153) ; rat ... Ar(24208) , Polb(29240)

Beschreibung

Anwendung

Cholesterol was used to prepare immune-stimulating complexes to enhance cellular and humoral responses. It was incorporated in animal feed to study the effect of cholesterol-rich diet.

Biochem./physiol. Wirkung

Hauptbestandteil biologischer Membranen; ca. 25% des gesamten Lipids im Gehirn ist Cholesterin.

Cholesterol is a lipid makes up about 20-25% of the structural components of the cell membranes. It determines the fluidity and permeability of the membrane, making it permeable to water but not to ions and protons. Cholesterol also regulates the functions of the transporters and signaling proteins present on the plasma membrane. The major sites of cholesterol synthesis are small intestine and liver.

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)