21882

5(6)-Carboxy-2′,7′-dichlorfluoreszein

BioReagent, suitable for fluorescence, ≥95% (TLC)

• Empirische Formel (Hill-System): C₂₁H₁₀Cl₂O₇
• CAS-Nummer: 111843-78-8
• Molekulargewicht: 445.21
• MDL-Nummer: MFCD00037452
• UNSPSC-Code: 12352108
• PubChem Substanz-ID: 57647948
• NACRES: NA.32

Eigenschaften

• Produktlinie: BioReagent
• Assay: ≥95% (TLC)
• Form: solid
• pKa: 5.1
• mp (Schmelzpunkt): ≥250 °C (lit.)
• Löslichkeit: DMF: soluble; DMSO: soluble; H₂O: soluble (pH ≥ 5)
• Fluoreszenz: λ_ex 504 nm; λ_em 529 nm in 0.1 M Tris pH 8.0
• Eignung: suitable for fluorescence
• SMILES String: OC(=O)c1ccc(c(c1)C(O)=O)C2=C3C=C(Cl)C(=O)C=C3Oc4cc(O)c(Cl)cc24.OC(=O)c5ccc(C(O)=O)c(c5)C6=C7C=C(Cl)C(=O)C=C7Oc8cc(O)c(Cl)cc68
• InChI: 1S/2C21H10Cl2O7/c22-13-4-11-17(6-15(13)24)30-18-7-16(25)14(23)5-12(18)19(11)10-3-8(20(26)27)1-2-9(10)21(28)29;22-13-4-11-17(6-15(13)24)30-18-7-16(25)14(23)5-12(18)19(11)9-2-1-8(20(26)27)3-10(9)21(28)29/h2*1-7,24H,(H,26,27)(H,28,29)
• InChIKey: WHFHRELKGQJJBQ-UHFFFAOYSA-N

Beschreibung

Anwendung

geeignet als pH-Indikator

5(6)-Carboxy-2′,7′-dichlorofluorescein may be used as a specific substrate/probe to study the identity, activity and specificity of multidrug resistance protein 2 (MRP2) molecules.

Sonstige Hinweise

Fluorescent intracellular pH indicator in the pH 4-5 range[1]

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves