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Sigma-Aldrich

Arsentrioxid

ACS reagent (primary standard)

Synonym(e):

Arsen(III)-oxid, Arsenigsäure-anhydrid

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About This Item

Empirische Formel (Hill-System):
As2O3
CAS-Nummer:
1327-53-3
Molekulargewicht:
197.84
EG-Nummer:
215-481-4
MDL-Nummer:
MFCD00003433
UNSPSC-Code:
12171602
PubChem Substanz-ID:
329753664
NACRES:
NB.24

Qualität

ACS reagent (primary standard)

Dampfdruck

0 hPa ( 66 °C)

Assay

99.95-100.05%

Form

powder

Eignung der Reaktion

reagent type: catalyst
core: arsenic

Glührückstand

≤0.02%

Löslichkeit

dilute HCl: insoluble ≤0.01%

Anionenspuren

S2-: passes test (lim. ~0.001%)
chloride (Cl-): ≤0.005%

Kationenspuren

Fe: ≤5 ppm
Pb: ≤0.002%
Sb: ≤0.05%

SMILES String

O=[As]O[As]=O

InChI

1S/As2O3/c3-1-5-2-4

InChIKey

IKWTVSLWAPBBKU-UHFFFAOYSA-N

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Allgemeine Beschreibung

Arsenic (III) oxide, also referred to as arsenic trioxide, is an amphoteric oxide that is used as a raw material to produce several arsenic-based compounds.

Anwendung

Arsenic (III) oxide is used
  • In the synthesis of arsenic pentafluoride (AsF5) by static fluorination method in a closed system.
  • In the preparation of arsenic-doped ZnO films by adding As2O3 to zinc acetate, 2-methoxyethanol, and monoethanolamine by sol-gel spin coating method.

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Skin Corr. 1B - STOT RE 1

Zielorgane

Respiratory system,Cardio-vascular system,Gastrointestinal tract

Lagerklassenschlüssel

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Sigma-Aldrich

S7400

Natrium(meta)arsenit

Arsen(III) Standard für ICP TraceCERT®, 1 g/L As(III) in hydrochloric acid (nominal concentration)

Supelco

72718

Arsen(III) Standard für ICP

Arsen(III)-chlorid 99.99% trace metals basis

Sigma-Aldrich

200077

Arsen(III)-chlorid

Xiao Liu et al.
Science China. Life sciences, 63(11), 1744-1754 (2020-05-10)
This study aimed to explore macrophage polarization in acute graft-versus-host disease after hematopoietic stem cell transplantation, and investigated if arsenic trioxide (ATO) could correct this imbalance. In the colon of GVHD mice, we found that the number of F4/80+iNOS+ cells
Shaohong Fang et al.
Cell death & disease, 12(1), 88-88 (2021-01-20)
Inducing autophagy and inhibiting apoptosis may provide a therapeutic treatment for atherosclerosis (AS). For the treatment of progressive AS, arsenic trioxide (ATO) has been used to coat vascular stents. However, the effect of ATO on autophagy of macrophages is still
Yuhua Fan et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 31(1), 80-91 (2013-02-01)
Arsenic trioxide (As2O3) is a highly effective agent for treatment of acute promyelocytic leukemia (APL). However, consecutively administered As2O3 induces serious adverse cardiac effects, including long QT syndrome (LQTs) and even sudden cardiac death. Previous studies have shown that genistein
Yanfei Jia et al.
PloS one, 8(1), e54774-e54774 (2013-02-06)
Alpha-fetoprotein (AFP)-producing gastric cancer (AFPGC), represented by the production of AFP, has a more aggressive behavior than common gastric cancer. The underlying mechanisms are not well understood. Arsenic trioxide (As(2)O(3)) is used clinically to treat acute promyelocytic leukemia(APL) and has
Liangchun Hao et al.
Journal of pediatric hematology/oncology, 35(2), e67-e70 (2013-02-16)
The aim of this study was to investigate the hepatotoxicity induced by arsenic trioxide (As2O3) at a therapeutic dose for pediatric acute promyelocytic leukemia (APL). A total of APL patients received As2O3 treatment by IV drip. Hepatotoxicity was monitored based
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