Daidzein-7-O-glucuronide is a conjugated polar metabolite of the soy isoflavone daidzein, present in blood and tissues following soy product consumption. Daidzein, circulating as its glucuronide or sulfate forms, influences various cellular processes and is utilized as a dietary supplement for addressing menopausal bone loss and cancer prevention. Recent studies have highlighted the importance of understanding the metabolism and disposition of isoflavones like daidzein and genistein in plasma, particularly regarding their role in preventing hormone-dependent diseases and their potential activation within target cells.
Anwendung
Daidzein-7-O-glucuronide can be employed for studying the metabolism and metabolomic pathways of daidzein isoflavone, particularly in the context of metabolomics, phytochemical, and biochemical research.
Leistungsmerkmale und Vorteile
Versatile and adaptable for a variety of research and metabolomics applications.
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Journal of agricultural and food chemistry, 66(49), 12941-12952 (2018-11-18)
Black soybeans are rich in isoflavones, which have several beneficial health effects. In this study, a validated method based on UHPLC-MS/MS was developed to screen black-soybean metabolites in rat urine, bile, and plasma and to quantify the compounds (daidzein, genistein
Archives of toxicology, 90(6), 1335-1347 (2016-02-04)
Soy isoflavones (IF) are in the focus of biomedical research since more than two decades. To assess their bioactivity, IF are investigated in rats and mice as a model. As the biological activity of IF is affected by their biotransformation
Ecotoxicology and environmental safety, 197, 110611-110611 (2020-04-16)
Efficient aquaculture is depending on sustainable protein sources. The shortage in marine raw materials has initiated a shift to "green aquafeeds" based on staple ingredients such as soy and wheat. Plant-based diets entail new challenges regarding fish health, product quality
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