PHR1701

Triamcinolon-Acetonid

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(e): Triamcinolonacetonid, 9α-Fluor-11β,16α,17α,21-tetrahydroxy-1,4-pregnadien-3,20-dion-16,17-acetonid, 9α-Fluor-16α-hydroxyprednisolon-16α,17α-acetonid
• Empirische Formel (Hill-System): C₂₄H₃₁FO₆
• CAS-Nummer: 76-25-5
• Molekulargewicht: 434.50
• EG-Nummer: 200-948-7
• MDL-Nummer: MFCD00056834
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329823564
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material; pharmaceutical secondary standard
• Qualitätsniveau: 300
• Agentur: traceable to Ph. Eur. T1900000; traceable to USP 1677002
• API-Familie: triamcinolone
• Analysenzertifikat (CofA): current certificate can be downloaded
• Verpackung: pkg of 1 g
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H]5OC(C)(C)O[C@@]45C(=O)CO
• InChI: 1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1
• InChIKey: YNDXUCZADRHECN-JNQJZLCISA-N
• Angaben zum Gen: human ... NR3C1(2908)

Beschreibung

Allgemeine Beschreibung

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Triamcinolone Acetonide is a glucocorticoid[1] and a derivative of pregnane, used mainly in the treatment of rheumatic disease, allergic and dermatologic symptoms.[2]

Anwendung

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Triamcinolone Acetonide may be used as a pharmaceutical standard for the determination of the analyte in drug dosage forms by high performance liquid chromatography[2][3] and spectrophotometry.[4]

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAC2813 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H302,H360
• P-Sätze: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Gefahreneinstufungen: Acute Tox. 4 Oral - Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable