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M9524

Supelco

Morphin -sulfat (Salz) -Lösung

1.0 mg/mL in methanol, drug standard

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About This Item

Empirische Formel (Hill-System):
C34H38N2O6 · H2SO4
CAS-Nummer:
64-31-3
Molekulargewicht:
668.75
EG-Nummer:
200-659-6
MDL-Nummer:
MFCD00069309
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329818093
NACRES:
NA.24

Qualität

drug standard

Qualitätsniveau

200

drug control

Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

Konzentration

1.0 mg/mL in methanol

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

pharmaceutical (small molecule)

Format

single component solution

Lagertemp.

−20°C

SMILES String

OS(O)(=O)=O.CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4O)c35.CN6CC[C@]78[C@H]9Oc%10c(O)ccc(C[C@@H]6[C@@H]7C=C[C@@H]9O)c8%10

InChI

1S/2C17H19NO3.H2O4S/c2*1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18;1-5(2,3)4/h2*2-5,10-11,13,16,19-20H,6-8H2,1H3;(H2,1,2,3,4)/t2*10-,11+,13-,16-,17-;/m00./s1

InChIKey

USAHOPJHPJHUNS-IFCNUISUSA-N

Angaben zum Gen

human ... OPRM1(4988)

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Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Zielorgane

Eyes

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 2

Flammpunkt (°F)

51.8 °F - closed cup

Flammpunkt (°C)

11 °C - closed cup

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Analysenzertifikate (COA)

Lot/Batch Number
SLCJ5561
SLCG5271
SLBZ9657
SLBQ5023V
SLBK9386V

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Laura S Stone et al.
PloS one, 9(10), e109903-e109903 (2014-10-10)
Opioids are used to manage all types of pain including acute, cancer, chronic neuropathic and inflammatory pain. Unfortunately, opioid-related adverse effects such as respiratory depression, tolerance, physical dependence and addiction have led to an underutilization of these compounds for adequate
Colin Harvey-Lewis et al.
Psychopharmacology, 232(5), 885-895 (2014-09-06)
Chronic opiate use is associated with increased impulsivity in both humans and animals, and previous studies suggest that acute morphine can increase impulsivity in non-dependent rats. However, the extent to which chronic opiate usage modulates the effect of acute morphine
Martin Guillot et al.
PloS one, 9(5), e97347-e97347 (2014-05-27)
In cats, osteoarthritis causes significant chronic pain. Chronicity of pain is associated with changes in the central nervous system related to central sensitization, which have to be quantified. Our objectives were 1) to develop a quantitative sensory testing device in
Lori N Eidson et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(40), 15952-15963 (2013-10-04)
The ventrolateral periaqueductal gray (vlPAG) is an integral locus for morphine action. Although it is clear that glia contribute to the development of morphine tolerance, to date, the investigation of their role has been limited to spinal and medullary loci.
Shilong Yang et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(43), 17534-17539 (2013-10-02)
Loss-of-function mutations in the human voltage-gated sodium channel NaV1.7 result in a congenital indifference to pain. Selective inhibitors of NaV1.7 are therefore likely to be powerful analgesics for treating a broad range of pain conditions. Herein we describe the identification
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