BP1094

Cyclophosphamid

British Pharmacopoeia (BP) Reference Standard

• Synonym(e): Cyclophosphamid Monohydrat, 2-[Bis-(2-chlorethyl)-amino]-tetrahydro-2H-1,3,2-oxazaphosphorin-2-oxid, Cytoxan
• Empirische Formel (Hill-System): C₇H₁₅Cl₂N₂O₂P · H₂O
• CAS-Nummer: 6055-19-2
• Molekulargewicht: 279.10
• Beilstein: 4678992
• MDL-Nummer: MFCD00149395
• UNSPSC-Code: 41116107
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: cyclophosphamide
• Form: crystalline
• Haltbarkeit: limited shelf life, expiry date on the label
• Hersteller/Markenname: BP
• mp (Schmelzpunkt): 49-51 °C (lit.)
• Anwendung(en): pharmaceutical; pharmaceutical small molecule
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: [H]O[H].ClCCN(CCCl)P1(=O)NCCCO1
• InChI: 1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2
• InChIKey: PWOQRKCAHTVFLB-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Cyclophosphamide BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Cyclophosphamide Oral Solution

Biochem./physiol. Wirkung

Cyclophosphamid ist ein Stickstofflostderivat, das in der Krebstherapie verbreitete Anwendung findet. Es führt zur Quervernetzung der DNA sowie zum Abbruch von Strängen und induziert Mutationen. Seine klinische Aktivität wird mit einer Abnahme der ALDH1-Aktivität (Aldehyd-Dehydrogenase 1) assoziiert.

Verpackung

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H301,H340,H350,H360FD
• P-Sätze: P202 - P264 - P270 - P280 - P301 + P310 - P405
• Gefahreneinstufungen: Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): 235.4 °F - closed cup
• Flammpunkt (°C): 113 °C - closed cup