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Merck

B1385

Supelco

Butoxamin -hydrochlorid

analytical standard, for drug analysis, mixture of diastereomers

Synonym(e):

α-[1-(tert.-Butylamino)-ethyl]-2,5-dimethoxy-benzylalkohol

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50 MG
CHF 167.00

CHF 167.00


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50 MG
CHF 167.00

About This Item

Empirische Formel (Hill-System):
C15H25NO3 · HCl
CAS-Nummer:
Molekulargewicht:
303.82
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

CHF 167.00


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Qualitätsniveau

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Format

neat

SMILES String

Cl.COc1ccc(OC)c(c1)C(O)C(C)NC(C)(C)C

InChI

1S/C15H25NO3.ClH/c1-10(16-15(2,3)4)14(17)12-9-11(18-5)7-8-13(12)19-6;/h7-10,14,16-17H,1-6H3;1H

InChIKey

URPAECSKKQLCII-UHFFFAOYSA-N

Allgemeine Beschreibung

Butoxamine hydrochloride is a β-andrenoceptor antagonist, which shows β2-selectivity.[1][2]

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral - Eye Irrit. 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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Die Dokumentenbibliothek aufrufen

Claudio Molinari et al.
Endocrinology, 148(8), 4080-4090 (2007-04-28)
Prolactin has been associated with many effects and has been implicated in the pathogenesis of pregnancy-related hypertensive disorders, although little is known about its vascular effects. The present study was designed to determine the primary effect of prolactin on regional
Nozomu Abe et al.
BioMed research international, 2020, 3214186-3214186 (2020-05-29)
Adrenaline quickly inhibits the release of histamine from mast cells. Besides β2-adrenergic receptors, several in vitro studies also indicate the involvement of α-adrenergic receptors in the process of exocytosis. Since exocytosis in mast cells can be detected electrophysiologically by the
Dong Zhang et al.
Pancreas, 38(1), 94-100 (2008-12-25)
Propranolol inhibited pancreatic cancer cell proliferation by blocking signaling through the beta-adrenoceptor. We hypothesized that propranolol may suppress pancreatic cancer cell growth through induction of apoptosis. The beta-adrenoceptor antagonist propranolol, beta1-adrenoceptor antagonist metoprolol, and beta2-adrenoceptor antagonist butoxamine were used to
Cardiovascular teratogenicity of terbutaline and ritodrine in the chick embryo
Lenselink R.D, et al.
American Journal of Obstetrics and Gynecology, 171(2), 501-506 (1994)
Jiayin Lu et al.
Stress (Amsterdam, Netherlands), 24(5), 514-528 (2020-12-08)
During pregnancy, uterus undergoes the environment adaptation as part of a program of development. In the world, one in four people worldwide suffer from mental illness, especially pregnant women. β-Adrenergic receptor (β-AR) is an important regulator that converts environmental stimuli

Questions

  1. Can B1385 be used in mice?

    1 answer
    1. This product has not been tested for in vitro or in vivo use and is intended to be used as an analytical standard. While the material is not suitable for human or veterinary use, other researchers have used this item successfully in mouse models. See the link below to review a publication that may be of interest:
      https://pmc.ncbi.nlm.nih.gov/articles/PMC7867244/

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