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Merck

46161

Supelco

Demeclocyclin -hydrochlorid Hydrat

VETRANAL®, analytical standard

Synonym(e):

Demethylchlortetracyclin -hydrochlorid

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About This Item

Empirische Formel (Hill-System):
C21H21ClN2O8 · HCl · xH2O
CAS-Nummer:
Molekulargewicht:
501.31 (anhydrous basis)
Beilstein:
5705221
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Produktlinie

VETRANAL®

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

clinical testing

Format

neat

Lagertemp.

2-8°C

SMILES String

O.Cl.CN(C)[C@H]1[C@@H]2C[C@@H]3[C@H](O)c4c(Cl)ccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O

InChI

1S/C21H21ClN2O8.ClH.H2O/c1-24(2)14-7-5-6-10(16(27)12-9(25)4-3-8(22)11(12)15(6)26)18(29)21(7,32)19(30)13(17(14)28)20(23)31;;/h3-4,6-7,14-15,25-26,28-29,32H,5H2,1-2H3,(H2,23,31);1H;1H2/t6-,7-,14-,15-,21-;;/m0../s1

InChIKey

LZJOUJFCRCXBBC-XZJYMHMKSA-N

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Allgemeine Beschreibung

Chemical structure: tetracycline

Anwendung

Demeclocycline hydrochloride hydrate may be used as an internal standard for the determination of:
  • Oxytetracycline and tetracycline in pig manure samples by ultra-high performance liquid chromatography (UHPLC) coupled to triple quadrupole mass spectrometer equipped with electrospray ionization source (QqQ-ESI-MS/MS) and dynamic multiple reaction monitoring (dMRM) mode of detection.
  • Oxytetracycline hydrochloride in dairy products by UHPLC-QqQ-ESI-MS/MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Rechtliche Hinweise

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Piktogramme

Health hazardExclamation mark

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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J Bousek et al.
Journal of environmental management, 223, 545-553 (2018-07-01)
The fate of four widely used veterinary antibiotics (doxycycline, flumequine, oxytetracycline and tetracycline) during manure upcycling was investigated at laboratory and pilot scale. The pilot was operated continuously, while the laboratory scale in batch mode. Both set-ups consisted of anaerobic
Development and Validation of a Multi-class UHPLC-MS/MS Method for Determination of Antibiotic Residues in Dairy Products
Schwaiger B, et al.
Food Analytical Methods, 14, 1417-1434 (2018)
B Athanassiadis et al.
Australian dental journal, 54(2), 141-146 (2009-05-29)
The aim of this study was to determine the in vitro antimicrobial activities of various endodontic medicaments and their bases against selected organisms using an agar diffusion assay. An agar well diffusion assay was used to test the antimicrobial action
P Abbott et al.
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Chengyu Dong et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 103, 179-186 (2012-12-25)
This study was designed to examine the interaction of demeclocycline (DMCTC) with human serum albumin (HSA) by multi-spectroscopic and molecular docking methods. The inner filter effect was corrected before we calculated the binding parameters. Fluorescence and UV-vis spectroscopy revealed that

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