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Clofibrat

analytical standard

Synonym(e):

2-(4-Chlorphenoxy)-2-methyl-propionsäure-ethylester, Ethyl-2-(4-chlorphenoxy)-2-methylpropionat

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About This Item

Empirische Formel (Hill-System):
C12H15ClO3
CAS-Nummer:
637-07-0
Molekulargewicht:
242.70
Beilstein:
1913459
EG-Nummer:
211-277-4
MDL-Nummer:
MFCD00000615
UNSPSC-Code:
77101502
PubChem Substanz-ID:
329756088
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

100

Assay

≥99.0% (GC)

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Brechungsindex

n20/D 1.502-1.504

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

SMILES String

CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1

InChI

1S/C12H15ClO3/c1-4-15-11(14)12(2,3)16-10-7-5-9(13)6-8-10/h5-8H,4H2,1-3H3

InChIKey

KNHUKKLJHYUCFP-UHFFFAOYSA-N

Angaben zum Gen

human ... PPARA(5465)

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Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Piktogramme

CorrosionExclamation mark
GHS05,GHS07

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

235.4 °F - closed cup

Flammpunkt (°C)

113 °C - closed cup

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Analysenzertifikate (COA)

Lot/Batch Number
BCCL4805
BCCK3724
BCCH5625
BCCB8431
BCBV7245

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Clofibrate.
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 24, 39-58 (1980-01-01)
[Fibrates: mechanism of action, effect on levels of lipids and lipoproteins, risk of coronary events. Part 1. Clofibrate, gemfibrosil, besafibrate].
L M Dobordzhginidze et al.
Kardiologiia, 44(2), 96-103 (2004-05-06)
Tao Xiong et al.
Indian pediatrics, 49(1), 35-41 (2012-02-10)
To evaluate the effect of clofibrate for unconjugated hyperbilirubinemia in neonates. A systematic review with meta-analysis of randomized controlled trials or quasi-randomized controlled trials was conducted to evaluate the clofibrate treatment in neonates with unconjugated hyperbilirubinemia. We followed the guidelines
S Oikawa et al.
Nihon rinsho. Japanese journal of clinical medicine, 52(12), 3285-3291 (1994-12-01)
Clofibrate has cholesterol- and triglyceride-lowering effect. They affect on the various points in the metabolic pathway of lipoproteins. They improve VLDL-synthesis in liver and increase the activity of LPL and hepatic TG lipase. As the results, HDL-cholesterol increases and LDL
G Calais et al.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 22(2), 99-103 (1991-10-01)
It is generally accepted that hypoxia is a common occurrence in many experimental and human tumours and that it is a major cause of local failure after radiotherapy. Many attempts have been made over the last years to eliminate this
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