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Supelco

Aflatoxin B1 -Lösung

2 μg/mL in acetonitrile, analytical standard

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About This Item

Empirische Formel (Hill-System):
C17H12O6
CAS-Nummer:
1162-65-8
Molekulargewicht:
312.27
Beilstein:
1269174
EG-Nummer:
200-835-2
MDL-Nummer:
MFCD00869647
UNSPSC-Code:
85151701
PubChem Substanz-ID:
329754767
NACRES:
NA.24

Qualität

analytical standard

Haltbarkeit

limited shelf life, expiry date on the label

Konzentration

2 μg/mL in acetonitrile

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

cleaning products
cosmetics
food and beverages
personal care

Format

single component solution

Lagertemp.

−20°C

SMILES String

[H][C@]12OC=C[C@@]1([H])c3c(O2)cc(OC)c4C5=C(C(=O)CC5)C(=O)Oc34

InChI

1S/C17H12O6/c1-20-10-6-11-14(8-4-5-21-17(8)22-11)15-13(10)7-2-3-9(18)12(7)16(19)23-15/h4-6,8,17H,2-3H2,1H3/t8-,17+/m0/s1

InChIKey

OQIQSTLJSLGHID-WNWIJWBNSA-N

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Allgemeine Beschreibung

Aflatoxin B1 is a mycotoxin found to be hepatocarcinogenic in nature. It has a strong affinity for the deoxyribonucleic acid (DNA) and binds to both native and denatured deoxyribonucleic acid (DNA) as indicated by spectroscopy and equilibrium dialysis results. This fungal metabolic product is commonly found in food and feed, contaminated by Aspergillus species.

The product is supplied in CERTAN® vial.

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Aflatoxin B1 solution may be used as an analytical reference standard for the determination of the analyte in meat, meat products, eggs and milk using high-performance liquid chromatography (HPLC) with fluorescence and ultraviolet detection.

Rechtliche Hinweise

CERTAN is a registered trademark of LGC Group

Ähnliches Produkt

Produkt-Nr.
Beschreibung
Preisangaben

32754

Aflatoxin B1, reference material

Piktogramme

FlameExclamation mark
GHS02,GHS07

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 2

Flammpunkt (°F)

35.6 °F - closed cup

Flammpunkt (°C)

2 °C - closed cup

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
BCCM3676
BCCM0155
BCCL6485
BCCL3579
BCCL0703

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Die Dokumentenbibliothek aufrufen

Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1.
McGlynn AK, et al.
Proceedings of the National Academy of Sciences of the USA, 92(6), 2384-2387 (1995)
Aflatoxin B1 induces the transversion of G-> T in codon 249 of the p53 tumor suppressor gene in human hepatocytes.
Aguilar F, et al.
Proceedings of the National Academy of Sciences of the USA, 90(18), 8586-8590 (1993)
M B Sporn et al.
Science (New York, N.Y.), 151(3717), 1539-1541 (1966-03-25)
Aflatoxin B(1) binds to both native and denatured DNA, as shown by spectroscopy and equilibrium dialysis. It also strongly inhibits incorporation of cytidine into rat liver nuclear RNA and lowers the RNA content of the nucleus. The extremle toxicity and
Anna Z Wec et al.
Cell host & microbe, 25(1), 39-48 (2019-01-11)
Passive administration of monoclonal antibodies (mAbs) is a promising therapeutic approach for Ebola virus disease (EVD). However, all mAbs and mAb cocktails that have entered clinical development are specific for a single member of the Ebolavirus genus, Ebola virus (EBOV)
Determination of aflatoxins in eggs, milk, meat and meat products using HPLC fluorescent and UV detectors.
Herzallah MS.
Food Chemistry, 114(3), 1141-1146 (2009)
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solution, 2 μg/mL in acetonitrile, analytical standard

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