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Dokumente

09293

Sigma-Aldrich

2-(3-Aminopropylamino)-ethanol

≥98.0% (GC)

Synonym(e):

N-(2-Hydroxyethyl)-trimethylendiamin

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About This Item

Lineare Formel:
NH2CH2CH2CH2NHCH2CH2OH
CAS-Nummer:
4461-39-6
Molekulargewicht:
118.18
Beilstein:
1734412
EG-Nummer:
224-718-0
MDL-Nummer:
MFCD00025617
UNSPSC-Code:
12352100
PubChem Substanz-ID:
329748756
NACRES:
NA.22

Qualitätsniveau

100

Assay

≥98.0% (GC)

Brechungsindex

n20/D 1.486

bp

250-252 °C (lit.)

Dichte

1.007 g/mL at 20 °C (lit.)

SMILES String

NCCCNCCO

InChI

1S/C5H14N2O/c6-2-1-3-7-4-5-8/h7-8H,1-6H2

InChIKey

GHKSKVKCKMGRDU-UHFFFAOYSA-N

Angaben zum Gen

rat ... Grin2a(24409)

Sonstige Hinweise

Inhibitor of the mammalian glycogen debranching enzyme; Photographic development accelerator

Piktogramme

CorrosionExclamation mark
GHS05,GHS07

Signalwort

Danger

H-Sätze

H314,H317

Gefahreneinstufungen

Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Lagerklassenschlüssel

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flammpunkt (°F)

296.6 °F

Flammpunkt (°C)

147 °C

Persönliche Schutzausrüstung

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Analysenzertifikate (COA)

Lot/Batch Number
BCBH2852V
1416158V
1416158
433010/1
382065/1

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B K Gillard et al.
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Stephany Y Tzeng et al.
International journal of nanomedicine, 6, 3309-3322 (2012-01-10)
Biodegradable poly(ester amine) (PEA)-based and poly(amido amine) (PAA)-based nanoparticles were developed for efficient in vitro siRNA delivery to human umbilical vein endothelial cells (HUVECs). They were screened, characterized, and compared with traditionally studied DNA-containing particles. Several of the polymeric nanoparticles
Panagiotis Mastorakos et al.
Journal of controlled release : official journal of the Controlled Release Society, 262, 37-46 (2017-07-12)
The discovery of powerful genetic targets has spurred clinical development of gene therapy approaches to treat patients with malignant brain tumors. However, lack of success in the clinic has been attributed to the inability of conventional gene vectors to achieve
Camila G Zamboni et al.
Journal of controlled release : official journal of the Controlled Release Society, 263, 18-28 (2017-03-30)
Hepatocellular carcinoma (HCC) is the third most deadly cancer in the US, with a meager 5-year survival rate of <20%. Such unfavorable numbers are closely related to the heterogeneity of the disease and the unsatisfactory therapies currently used to manage
Antonella Mangraviti et al.
ACS nano, 9(2), 1236-1249 (2015-02-03)
Biodegradable polymeric nanoparticles have the potential to be safer alternatives to viruses for gene delivery; however, their use has been limited by poor efficacy in vivo. In this work, we synthesize and characterize polymeric gene delivery nanoparticles and evaluate their

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