AG774

Orexin-A, control peptide for AB3098

• UNSPSC-Code: 12352200
• eCl@ss: 32160405
• NACRES: NA.28

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Form: liquid
• Hersteller/Markenname: Chemicon^®
• Methode(n): inhibition assay: suitable (peptide)
• NCBI-Hinterlegungsnummer: NM_001524.1
• UniProt-Hinterlegungsnummer: O43612

Beschreibung

Allgemeine Beschreibung

18 amino acid peptide from the amino terminus of mouse Orexin-A.

Orexin-A control peptide.

Several peptides associated with feeding behavior have been reported recently. Orexins (Orexin-A and Orexin-B) are a family of hypothalamic neuropeptides selectively expressed in the hypothalamus (1). Orexin-A and Orexin-B are derived from the same precursor (Prepro-orexin) by proteolytic cleavage. Prepro-orexin is an 130 aa peptide with a putative 33 aa secretory sequence, a hydrophobic core followed by residues with small polar side chains. The expression was detected in brain and to a small extent in testis (1). These neuropeptides bind and activate two closely related Orexin receptors--G protein coupled receptors (GPCRs) OX1R and OX2R.

Anwendung

Blocking peptide for AB3098.

Optimal working concentration must be determined by the end user.

Physikalische Form

Liquid in PBS, pH 7.5

Lagerung und Haltbarkeit

Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 2