580553

(±)-Taxifolin hydrate

An antioxidant flavonoid that scavenges superoxide (1.5 x 10⁵ M⁻¹ s⁻¹) and suppresses the cytotoxicity of superoxide and hydrogen peroxide in Chinese hamster V79 cells.

• Synonym(e): 3,3′,4′,5,7-Pentahydroxydihydroflavone Hydrate, Dihydroquercetin Hydrate, 3,3′,4′,5,7-Pentahydroxyflavanone hydrate, Dihydroquercetin hydrate
• Empirische Formel (Hill-System): C₁₅H₁₂O₇ · xH₂O
• CAS-Nummer: 24198-97-8
• Molekulargewicht: 304.25 (anhydrous basis)
• MDL-Nummer: MFCD11044454
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95% (HPLC)
• Form: solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; protect from light
• Farbe: white to off-white
• Löslichkeit: ethanol: 20 mg/mL
• Versandbedingung: ambient
• Lagertemp.: 2-8°C
• SMILES String: O.O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c3ccc(O)c(O)c3
• InChI: 1S/C15H12O7.H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;/h1-5,14-19,21H;1H2/t14-,15+;/m0./s1
• InChIKey: DNQPGSVMBPSRIR-LDXVYITESA-N

Beschreibung

Allgemeine Beschreibung

An antioxidant flavonoid that scavenges superoxide (1.5 x 10⁵ M^-1 s^-1) and suppresses the cytotoxicity of superoxide and hydrogen peroxide in Chinese hamster V79 cells.

An antioxidant flavonoid that suppresses the cytotoxicity of superoxide ions and hydrogen peroxide in Chinese hamster V79 cells.

Biochem./physiol. Wirkung

Cell permeable: no

Flavonoid, antioxidant. Inhibits lipogenesis in cancer cells, most likely by targeting fatty acid synthase activity.

Primary Target
An antioxidant flavonoid that scavenges superoxide

Product does not compete with ATP.

Reversible: no

Verpackung

Packaged under inert gas

Warnhinweis

Toxicity: Harmful (C)

Sonstige Hinweise

Kostyuk, V.A., et al. 1998. Arch. Biochem. Biophys. 355, 43.
Bors, W., et al. 1995. Free Radic. Biol. Med. 19, 45.
Nakayama, T., et al. 1994. Cancer Res. 54, 1991s.
Nakayama, T., et al. 1993. Biochem. Pharmacol. 45, 265.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable