5.05873

(R)-Baclofen

• Synonym(e): (R)-Baclofen, STX 209, GABA _B Agonist, Baclofen, Arbaclofen, STX 209, GABA_B Agonist, Baclofen, Arbaclofen
• Empirische Formel (Hill-System): C₁₀H₁₂ClNO₂
• CAS-Nummer: 69308-37-8
• Molekulargewicht: 213.66
• UNSPSC-Code: 12352200

Eigenschaften

• Assay: ≥98% (HPLC)
• Qualitätsniveau: 100
• Form: solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; protect from light
• Farbe: off-white
• Löslichkeit: water: soluble
• Lagertemp.: 2-8°C
• InChI: 1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)
• InChIKey: KPYSYYIEGFHWSV-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

A selective agonist of GABA_B receptors that is shown to activate K+ conductance in hippocampal neurons. Also acts as an antispastic agent and a skeletal muscle relaxant. It is also an experimental drug to treat autism.

Biochem./physiol. Wirkung

Primary Target
GABA_B

Warnhinweis

Toxicity: Toxic (F)

Rekonstituierung

Following reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.

Sonstige Hinweise

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Sodickson, D.L., et al., 1996. J. Neurosci.16, 6374.

Ahuja, S. et al., 1985. Analytical Profile of Drug Substances14, 527.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301
• P-Sätze: P264 - P270 - P301 + P310 - P405 - P501
• Gefahreneinstufungen: Acute Tox. 3 Oral
• Lagerklassenschlüssel: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable