220411

Chenodeoxycholic Acid, Sodium Salt

Bile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets. Induces a permeability transition in freshly isolated rat liver mitochondria.

• Synonym(e): Chenodeoxycholic Acid, Sodium Salt
• Empirische Formel (Hill-System): C₂₄H₃₉O₄ · Na
• CAS-Nummer: 2646-38-0
• Molekulargewicht: 414.55
• MDL-Nummer: MFCD00065452
• UNSPSC-Code: 12161902
• NACRES: NA.21

Eigenschaften

• Qualitätsniveau: 100
• Assay: >95% (TLC)
• Form: solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; desiccated (hygroscopic)
• Farbe: white
• Löslichkeit: water: 20 mg/mL; aqueous buffer: soluble
• Kationenspuren: heavy metals: <10 ppm
• Versandbedingung: ambient
• Lagertemp.: 15-25°C
• InChI: 1S/C24H40O4.Na/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26;/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-;/m1./s1
• InChIKey: WDFRNBJHDMUMBL-OICFXQLMSA-M

Beschreibung

Allgemeine Beschreibung

Bile acid that has been shown to increase intracellular Ca²⁺ in isolated rat hepatocyte couplets.

Bile acid that has been shown to increase intracellular Ca²⁺ in isolated rat hepatocyte couplets. Induces a permeability transition in freshly isolated rat liver mitochondria.

Warnhinweis

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

Sonstige Hinweise

Rolo, A.P., et al. 2001. Biosci. Rep.21, 73.
Thibault, N., and Ballet, F. 1993. Biochem. Pharmacol. 45, 289.
Roda, A., et al. 1990. J. Lipid Res.31, 1433.
Spivak, W., et al. 1988. Biochem. J.252, 275.
Hisadome, T., et al. 1980. Gastroenterol. Jpn.15, 257.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H301,H361d
• P-Sätze: P202 - P264 - P270 - P280 - P301 + P310 - P405
• Gefahreneinstufungen: Acute Tox. 3 Oral - Repr. 2
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable