218753

Caspase-5 Inhibitor I

Single spot by TLC, solid, Caspase-5 inhibitor, Calbiochem^®

• Synonym(e): Caspase-5 Inhibitor I, Z-WE(OMe)HD(OMe)-FMK
• Empirische Formel (Hill-System): C₃₇H₄₂FN₇O₁₀
• Molekulargewicht: 763.77
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• product name: Caspase-5 Inhibitor I, Z-WEHD-FMK is a cell-permeable, potent, irreversible caspase-5 inhibitor, that also inhibits the activity of Caspase 1, 4, and 8.
• Qualitätsniveau: 100
• Form: solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; desiccated
• Farbe: white
• Löslichkeit: DMSO: 5 mg/mL
• Versandbedingung: ambient
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

A potent, cell-permeable and irreversible inhibitor of caspase-5 (ICE_rel-III, TY), as well as caspase-1 and caspase-4.

A potent, cell-permeable, and irreversible inhibitor of caspase-5. Strongly inhibits caspase-1. Also inhibits caspase-4 and caspase-8.

Biochem./physiol. Wirkung

Cell permeable: yes

Primary Target
caspase-1, caspase-4, caspase-5, caspase-8

Reversible: no

Warnhinweis

Toxicity: Standard Handling (A)

Sequenz

Z-Trp-Glu(OMe)-His-Asp(OMe)-CH₂F*

Physikalische Form

Supplied as a trifluoroacetate salt.

Rekonstituierung

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.

Hinweis zur Analyse

single spot by TLC

Sonstige Hinweise

Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Rano, T., et al. 1997. Chem. Biol. 4, 149.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable