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07-001

Sigma-Aldrich

Anti-p47-phox Antibody

serum, Upstate®

Synonym(e):

Anti-Anti-CGD1, Anti-Anti-NCF1A, Anti-Anti-NOXO2, Anti-Anti-SH3PXD1A, Anti-Anti-p47phox

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

serum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

human

Hersteller/Markenname

Upstate®

Methode(n)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotyp

IgG

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... NCF1(653361)

Spezifität

Recognizes p47 phox.

Immunogen

GST fusion protein corresponding to full-length human p47-phox

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Oxidativer Stress
Anti-p47-phox Antibody detects level of p47-phox & has been published & validated for use in IC, IP & WB.

Qualität

routinely evaluated by immunoblot on RIPA lysates from HL-60 cells

Zielbeschreibung

47 kDa

Physikalische Form

Unpurified
Immunoaffinity Purified immunoglobulin in 0.2M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide, 5mg/ml BSA before the addition of glycerol to 30%

Lagerung und Haltbarkeit

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hinweis zur Analyse

Control
HL-60 cell lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Molecular diagnosis of X-linked chronic granulomatous disease in Iran.
S Teimourian, Z Rezvani, M Badalzadeh, C Kannengiesser, D Mansouri, M Movahedi et al.
International Journal of Hematology null
Y Li et al.
Redox biology, 22, 101143-101143 (2019-03-22)
First described as essential to the phagocytic activity of leukocytes, Nox2-derived ROS have emerged as mediators of a range of cellular and tissue responses across species from salubrious to deleterious consequences. Knowledge of their role in inflammation is limited, however.
Eduardo Rebelato et al.
Life sciences, 91(7-8), 244-249 (2012-07-24)
NADPH oxidase (NOX) is a known source of superoxide anions in phagocytic and non-phagocytic cells. In this study, the presence of this enzyme in human pancreatic islets and the importance of NADPH oxidase in human β-cell function were investigated. In
Dena Parsa et al.
Molecular medicine (Cambridge, Mass.), 28(1), 60-60 (2022-06-07)
African Americans (AAs) are disproportionately affected by cardiovascular disease (CVD), they are 20% more likely to die from CVD than whites, chronic exposure to inflammation and oxidative stress contributes to CVD. In previous studies, enhancing parasympathetic cholinergic activity has been
Localization of a constitutively active, phagocyte-like NADPH oxidase in rabbit aortic adventitia: enhancement by angiotensin II
Pagano, P J, et al
Proceedings of the National Academy of Sciences of the USA, 94, 14483-14488 (1997)

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