880670P

C8 PEG750 Ceramide

Avanti Research^™ - A Croda Brand 880670P, powder

• Synonym(e): N-octanoyl-sphingosine-1-{succinyl[methoxy(polyethylene glycol)750]}
• CAS-Nummer: 212116-76-2
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Form: powder
• Verpackung: pkg of 1 × 25 mg (880670P-25mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 880670P
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: O=C(CCC(OC[C@]([H])(NC(CCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC)=O)OOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC.C=C
• InChIKey: NVPZJFQMNPKURK-KIAKULPZSA-N

Beschreibung

Allgemeine Beschreibung

Ceramide is one of the products of sphingolipid metabolism. The ceramides differ in their acyl chain length.[1]

Anwendung

C8 PEG750 Ceramide has been used in ceramide liposome formulation to test a method for pH-dependent fusion between liposomes and cellular membranes using a pH low insertion peptide.[2] It is also suitable for use in nanoliposomal formulation.[3][4]

Biochem./physiol. Wirkung

Poly-ethylene glycol (PEG) conjugated to ceramides are applicable as liposomal carriers, enclosing drug molecules. They are known to increase the circulation longevity of the drug due to its neutral surface electrostatic charge. This is inferred to decrease the negative surface charge of the liposomes preventing the release of positively charged encapsulated drug molecule.[5]

Verpackung

5 mL Amber Glass Screw Cap Vial (880670P-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3