870865P

BMP22

Avanti Research^™ - A Croda Brand, powder

• Synonym(e): 4-pentadecylbenzylphosphonic acid
• Empirische Formel (Hill-System): C₂₂H₃₉O₃P
• CAS-Nummer: 1306684-90-1
• Molekulargewicht: 382.52
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Assay: 99% (TLC)
• Form: powder
• Verpackung: pkg of 1 × 1 mg (870865P-1mg); pkg of 1 × 5 mg (870865P-5mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand
• Lipid-Typ: bioactive lipids
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: CCCCCCCCCCCCCCCC1=CC=C(CP(O)(O)=O)C=C1

Beschreibung

Allgemeine Beschreibung

BMP (bis(monoacylglycerol)phosphate) is synthesized from phosphatidylglycerol (PG) in alveolar macrophages. BMP is a unique phospholipid having a glycerol phosphate ester at sn-1 position rather than sn-3 and has one acyl group attached to each of the glycerol moieties. The acyl groups of BMP is rich in polyunsaturated species.

Biochem./physiol. Wirkung

BMP (bis(monoacylglycerol)phosphate) (BMP) is found in the retinal pigment epithelium of healthy human retina. BMP lipids regulates cholesterol level in endosomes. It is implicated in endosomal/lysosomal storage diseases like Niemann-Pick and neuronal ceroid lipofuscinosis diseases. BMP22/4PBPA is a small molecule inhibitor of autotaxin (ATX). 4PBPA has relatively a longer half-life and also reduces the lysophosphatidic acid concentration in plasma. BMP22 is implicated in reducing the bone erosion and systemic bone loss.

Verpackung

5ML Glass Amber Screw Cap Vial (870865P-1MG)

5ML Glass Amber Screw Cap Vial (870865P-5MG)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable