870600C

PAzePC

Avanti Research^™ - A Croda Brand 870600C

• Synonym(e): 1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine
• Empirische Formel (Hill-System): C₃₃H₆₄NO₁₀P
• CAS-Nummer: 117746-89-1
• Molekulargewicht: 665.84
• MDL-Nummer: MFCD03412020
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Form: liquid
• Verpackung: pkg of 1 × 1 mL (870600C-1mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 870600C
• Konzentration: 1 mg/mL (870600C-1mg)
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCC(O)=O)=O)COC(CCCCCCCCCCCCCCC)=O)=O
• InChI: 1S/C33H64NO10P/c1-5-6-7-8-9-10-11-12-13-14-15-18-21-24-32(37)41-28-30(29-43-45(39,40)42-27-26-34(2,3)4)44-33(38)25-22-19-16-17-20-23-31(35)36/h30H,5-29H2,1-4H3,(H-,35,36,39,40)/t30-/m1/s1
• InChIKey: GHQQYDSARXURNG-SSEXGKCCSA-N

Beschreibung

Allgemeine Beschreibung

1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine (PAzePC) has carboxyl groups at the end of their truncated sn-2 chains.[1]

Anwendung

1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine (PAzePC) may be used:,as an oxidized lipid dopant in liposomes for investigating the relationship between the permeation of H2O2 and the structure of lipid membranes[2], as a substrate for lysosomal phospholipase A2 during the study of structural basis of lysosomal phospholipase A2 inhibition by Zn2+[3], in the preparation of large unilamellar vesicles (LUVs) and giant unilamellar vesicles (GUVs).[4]

Biochem./physiol. Wirkung

1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine (PAzePC) is an oxidized lipid. PAzePC acts as an inter- H2O2 permeation promoter.[2] It serves as a drug target for antipsychotic drugs and antimicrobial agents in cells under oxidative stress at inflammatory sites.[1] PAzePC facilitates permeabilization of Bax associated-mitochondrial membranes under oxidative stress.[4]

Verpackung

5 mL Clear Glass Sealed Ampule (870600C-1mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H302,H315,H319,H331,H336,H351,H361d,H372
• P-Sätze: P201 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Zielorgane: Central nervous system, Liver,Kidney
• Lagerklassenschlüssel: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): does not flash
• Flammpunkt (°C): does not flash