850697P

06:0 PE

1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine, powder

• Synonym(e): PE(6:0/6:0)
• Empirische Formel (Hill-System): C₁₇H₃₄NO₈P
• CAS-Nummer: 96893-06-0
• Molekulargewicht: 411.43
• UNSPSC-Code: 51191904
• NACRES: NA.25

Eigenschaften

• Assay: >99% (TLC)
• Form: powder
• Verpackung: pkg of 1 × 25 mg (850697P-25mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 850697P
• Lipid-Typ: cardiolipins; phospholipids
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: [H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCC)=O)COC(CCCCC)=O
• InChI: 1S/C17H34NO8P/c1-3-5-7-9-16(19)23-13-15(26-17(20)10-8-6-4-2)14-25-27(21,22)24-12-11-18/h15H,3-14,18H2,1-2H3,(H,21,22)/t15-/m1/s1
• InChIKey: PELYUHWUVHDSSU-OAHLLOKOSA-N

Beschreibung

Allgemeine Beschreibung

06:0 Phosphatidylethanolamine (PE) is a water-soluble short-chain glycero-phospholipid. It is primarily found in the inner leaflet of the plasma membrane.[1]

Phosphatidylethanolamine (PE), an abundant phospholipid in the inner mitochondrial membrane accounts for 15–25% of the total lipid in the cells of mammals.[2]

Anwendung

06:0 PE (1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine/DHPE) may be used:

• as a substrate for glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP) in specificity assay[3]
• as a phosphoethanolamine (PE) standard in liquid chromatographic analysis of milk phospholipids[4]
• as a phospholipid substrate to study the kinetic parameters for the glucose transporter type 4 (Glu4) mutants[5]

06:0 Phosphatidylethanolamine (PE) has been used as a ligand in the co-crystallization of broadly neutralizing anti-HIV antibody 4E10.[1] It has also been used as one of the phospholipids (PLs) standards for the analysis of bovine milk PL classes by normal-phase high-performance liquid chromatography (NP-HPLC).[6]

Biochem./physiol. Wirkung

06:0 Phosphatidylethanolamine (PE) plays an important role in various cellular processes such as autophagy, cell division and protein folding. In addition it also acts as a precursor for the synthesis of several protein modifications and as an intermediate in the synthesis of other glycerophospholipids.[7]

Phosphoethanolamine (PE) serves as a precursor in membrane phospholipid biosynthesis.[8] Phosphatidylethanolamine controls membrane fluidity in eukaryotic cells.[9]

Verpackung

5 mL Clear Glass Sealed Ampule (850697P-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids