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840435P

Avanti

12:0 PG

Avanti Research™ - A Croda Brand

Synonym(e):

1,2-didodecanoyl-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); DLPG; PG(12:0/12:0)

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25 MG
CHF 106.00
200 MG
CHF 313.00

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25 MG
CHF 106.00
200 MG
CHF 313.00

About This Item

Empirische Formel (Hill-System):
C30H58O10PNa
CAS-Nummer:
322647-27-8
Molekulargewicht:
632.74
MDL-Nummer:
MFCD00135194
UNSPSC-Code:
51191904
NACRES:
NA.25

CHF 106.00

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Beschreibung

1,2-dilauroyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt)

Assay

>99% (TLC)

Form

powder

Verpackung

pkg of 1 × 200 mg (840435P-200mg)
pkg of 1 × 25 mg (840435P-25mg)

Hersteller/Markenname

Avanti Research™ - A Croda Brand

Lipid-Typ

cardiolipins
phospholipids

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCC)COC(=O)CCCCCCCCCCC)OCC(O)CO

InChI

1S/C30H59O10P.Na/c1-3-5-7-9-11-13-15-17-19-21-29(33)37-25-28(26-39-41(35,36)38-24-27(32)23-31)40-30(34)22-20-18-16-14-12-10-8-6-4-2;/h27-28,31-32H,3-26H2,1-2H3,(H,35,36);/q;+1/p-1/t27?,28-;/m1./s1

InChIKey

CIRSYGHBBDDURM-AMRYRHMLSA-M

Allgemeine Beschreibung

Phosphatidylglycerol (PG) is one of the most important lipid, found in Gram-positive bacteria. It has odd-numbered branched-chain fatty acids as acyl chains.[1] This phospholipid is ubiquitously present in the membranes of several organisms.[2] 12:0 PG (1,2-dilauroyl-sn-glycero-3-phospho-(1′-rac-glycerol)/DLPG) is an anionic phospholipid. It is an anionic analogue of the zwitterionic phospholipid, dilauroyl phosphatidylcholine (DLPC).[3]

Anwendung

12:0 PG (1,2-dilauroyl-sn-glycero-3-phospho-(1′-rac-glycerol)) has been used in monomolecular films as representative lipid component of eukaryotic membranes to study the generality of the non-steroidal anti-inflammatory drug (NSAID)-related effect.[4] It may also be used:
  • in the preparation of liposomes for PagP folding assays[5]
  • as a component in pyrene labeleld liposomes[6]
  • to construct liposome/lipid vesicle[7]

Biochem./physiol. Wirkung

Phosphatidylglycerol (PG) is known to participate in photosynthesis.[2]

Verpackung

5 mL Amber Glass Screw Cap Vial (840435P-200mg)
5 mL Amber Glass Screw Cap Vial (840435P-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Lagerklassenschlüssel

11 - Combustible Solids

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

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10:0 PG 1,2-didecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), powder

Avanti

840434P

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Gerardino D'Errico et al.
Biochimica et biophysica acta, 1778(12), 2710-2716 (2008-08-19)
There is mounting evidence that the lipid matrix of neuronal cell membranes plays an important role in the accumulation of beta-amyloid peptides into senile plaques, one of the hallmarks of Alzheimer's disease (AD). With the aim to clarify the molecular
Lloyd Ryan et al.
The Journal of biological chemistry, 288(28), 20162-20172 (2013-06-06)
Antimicrobial or host defense peptides are innate immune regulators found in all multicellular organisms. Many of them fold into membrane-bound α-helices and function by causing cell wall disruption in microorganisms. Herein we probe the possibility and functional implications of antimicrobial
FATS vert Occurrence
Encyclopedia of food sciences and nutrition, 2293-2296 (2003)
Lindsay M McMorran et al.
Journal of molecular biology, 425(17), 3178-3191 (2013-06-26)
Although many periplasmic folding factors have been identified, the mechanisms by which they interact with unfolded outer membrane proteins (OMPs) to promote correct folding and membrane insertion remain poorly understood. Here, we have investigated the effect of two chaperones, Skp
Carolina Medina Amado et al.
Biochimica et biophysica acta. Biomembranes, 1862(2), 183135-183135 (2019-11-19)
The mechanism of action of the anti-Listeria peptide enterocin CRL35 was studied with biophysical tools by using lipid mixtures that mimicked Gram-positive plasma membranes. Langmuir monolayers and infrared spectroscopy indicated that the peptide readily interacted with phospholipid assembled in monolayers
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Artikel

Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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