ALD00578

2-Bromopyridin-3-yl sulfurofluoridate

95%

• Empirische Formel (Hill-System): C₅H₃BrFNO₃S
• Molekulargewicht: 256.05
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329772722
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 95%
• Form: liquid
• Brechungsindex: n20/D 1.5160
• Übergangstemp.: flash point >230 °F
• Dichte: 1.8283 g/mL
• Lagertemp.: 2-8°C

Beschreibung

Anwendung

2-Bromopyridin-3-yl sulfurofluoridate can be used in the Pd-catalyzed Suzuki-Miyuara cross-coupling reaction. The fluorosulfate functionality was shown by Sharpless and coworkers to have distinct reactivity in comparison to other functional groups used in Suzuki-Miyuara reactions, such as bromides, chlorides and triflates. This inherent property provides a strong potential for selective Suzuki-Miyuara couplings for chemoselective reaction sequences.

Sonstige Hinweise

Chemoselective Synthesis of Polysubstituted Pyridines from Heteroaryl Fluorosulfates

Palladium-Catalyzed, Ligand-Free Suzuki Reaction in Water Using Aryl Fluorosulfates

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H314
• P-Sätze: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Skin Corr. 1B
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3