Direkt zum Inhalt
Merck

797545

Sigma-Aldrich

6-Boc-1-oxa-6-azaspiro[3.3]heptan-3-one

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About This Item

Empirische Formel (Hill-System):
C10H15NO4
CAS-Nummer:
Molekulargewicht:
213.23
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:

Form

solid

Lagertemp.

2-8°C

SMILES String

O=C1C2(CN(C(OC(C)(C)C)=O)C2)OC1

InChI

1S/C10H15NO4/c1-9(2,3)15-8(13)11-5-10(6-11)7(12)4-14-10/h4-6H2,1-3H3

InChIKey

OIFFGPWHSKSMTM-UHFFFAOYSA-N

Anwendung

Spirocyclic building block is part of a series of advanced angular[3.3]heptanes developed by Carreira and coworkers.

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Artikel

Spirocyclic modules containing four-membered rings are currently of growing interest to discovery chemists.

Verwandter Inhalt

The Carreira Research Group is focused on expanding and creating access to uncharted landscape in chemical space. In joint efforts with SpiroChem, Carreira develops innovative spirocyclic building blocks, seeking to make them available to the community at large. Molecules constructed from these building blocks take on unique three-dimensional profiles due to the underlying spirocyclic scaffold, enriched by the presence of diverse combinations of exit vectors as sites for functionalization. Importantly, the spirocyclic building blocks possess physicochemical properties useful in the drug discovery process. Thus, drug leads can be tuned through appending these subunits to the periphery of a given scaffold. Moreover, these compact modules represent a useful collection of unprecedented inputs for fragment-based libraries. In all applications, the inherent novelty of the structure affords researchers new opportunities to run wild in their designs and avenues to chemical space – with their imagination as the sole limitations. We are proud to partner in the efforts to make these building blocks widely available.

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