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Sigma-Aldrich

Polyethylenimin, linear

average Mn 5,000, PDI ≤1.3

Synonym(e):

PEI

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About This Item

Lineare Formel:
(CH2CH2NH)n
CAS-Nummer:
9002-98-6
UNSPSC-Code:
12162002
NACRES:
NA.23

Form

solid

Mol-Gew.

average Mn 5,000

mp (Schmelzpunkt)

54-59 °C

PDI

≤1.3

Lagertemp.

2-8°C

InChI

1S/C2H5N/c1-2-3-1/h3H,1-2H2

InChIKey

NOWKCMXCCJGMRR-UHFFFAOYSA-N

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Allgemeine Beschreibung

All polyethylene imine polymers are hydrophilic and may contain approx. 30% hydrated water.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H315,H319

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Prashanth K B Nagesh et al.
Cancers, 10(9) (2018-08-29)
The therapeutic application of microRNA(s) in the field of cancer has generated significant attention in research. Previous studies have shown that miR-205 negatively regulates prostate cancer cell proliferation, metastasis, and drug resistance. However, the delivery of miR-205 is an unmet
Marco Hoffmann et al.
International journal of molecular sciences, 21(6) (2020-03-28)
Highly efficient, biocompatible, and fast nucleic acid delivery methods are essential for biomedical applications and research. At present, two main strategies are used to this end. In non-viral transfection liposome- or polymer-based formulations are used to transfer cargo into cells
Laura R H Ip et al.
Oncotarget, 6(12), 10548-10562 (2015-04-15)
Treatment options for ovarian cancer patients remain limited and overall survival is less than 50% despite recent clinical advances. The lipid phosphatase inositol polyphosphate 4-phosphatase type II (INPP4B) has been described as a tumor suppressor in the PI3K/Akt pathway with

Artikel

Delivery of Nucleic Acids Using Polymers

Delivery of Nucleic Acids Using Polymers

Functionalized PEI and Its Role in Gene Therapy

Gene therapy has become one of the most discussed techniques in biomedical research in recent years.

Nanoparticle-Based Drug and Gene Delivery for Tumor Targeting

Professor Yoshiki Katayama (Kyushu University, Japan) discusses recent advances in drug delivery systems and strategies that exploit the EPR effect, with a special focus on stimuli-responsive systems based on novel materials.

Progress on Nonviral Delivery for CRISPR/Cas9

CRISPR/Cas9 delivery via nonviral nanoparticles shows promising advancements for gene editing in disease treatment.

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