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Poly(ethylenglycol)methyletherthiol

average MN 6,000, chemical modification reagent thiol reactive, methoxy, thiol

Synonym(e):

Methoxy-PEG-thiol, Methoxypolyethylenglykol-thiol, PEG-thiol, mPEG-thiol

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1 G
CHF 276.00
5 G
CHF 916.00

CHF 276.00

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1 G
CHF 276.00
5 G
CHF 916.00

About This Item

Lineare Formel:
CH3O(CH2CH2O)nCH2CH2SH
UNSPSC-Code:
12162002
NACRES:
NA.23

CHF 276.00

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Produktbezeichnung

Poly(ethylenglycol)methyletherthiol, average Mn 6,000

Form

solid

Qualitätsniveau

100

Mol-Gew.

average Mn 6,000

Eignung der Reaktion

reagent type: chemical modification reagent
reactivity: thiol reactive

mp (Schmelzpunkt)

56-61 °C

Mw/Mn

≤1.2

Ω-Ende

thiol

α-Ende

methoxy

Polymerarchitektur

shape: linear
functionality: monofunctional

Versandbedingung

dry ice

Lagertemp.

−20°C

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Allgemeine Beschreibung

Poly(ethylenglycol)methyletherthiol (mPEG-Thiol)ist ein biokompatibles Polymer mit endständigem Thiol, das verbreitet für die Oberflächenfunktionalisierungvon Gold-Nanopartikeln eingesetzt wird. Thioleinheiten binden mit hoher Affinitätan Goldoberflächen, indem sie eine selbstorganisierte Monoschicht (SAM) durch diekovalente Thiolat–Metall-Bindung bilden. Mit mPEG-Thiol beschichtete Au-Nanopartikel werdenim Bereich der Biosensoren und Arzneimittelabgabesysteme eingesetzt.

Anwendung

Mit Poly(ethylenglycol)methyletherthiol beschichtete Au-Nanopartikel können zum Bestimmen von Melamin T. durch ein optisches Verfahren eingesetzt werden. Es kann auch zum Herstellen von schaltbaren Supernetzmittel-Membranen fürdie Trennung von Öl/Wasser eingesetzt werden.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
MKCW4612
MKCT8162
MKCV0351
MKCT0449
MKCQ8192

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Die Dokumentenbibliothek aufrufen

Amina Ghorbel et al.
Bioelectrochemistry (Amsterdam, Netherlands), 137, 107642-107642 (2020-09-28)
The use of conductive nanoparticles (NPs) was previously proposed as a way to locally amplify the electric field (EF) intensity at the cell membrane to enhance cell electroporation. To achieve this, a close distance between the NPs and the cell
Jairo Pinto Oliveira et al.
Scientific reports, 9(1), 13859-13859 (2019-09-27)
Antibody-coated nanoparticles have recently attracted considerable attention, with the focus falling on diagnostics. Nevertheless, controlled antibody bioconjugation remains a challenge. Here, we present two strategies of bioconjugation with the aim of evaluating the best approach for the coupling of antibodies

Artikel

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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