673927

Ethyl N-Boc-4-Methylpiperidin-4-Carboxylat

97%

• Synonym(e): 1-tert-Butoxycarbonyl-4-methylpiperidine-4-carboxylic acid ethyl ester, 4-Methyl-1,4-piperidinedicarboxylic acid 1-(1,1-dimethylethyl) 4-ethyl ester
• Empirische Formel (Hill-System): C₁₄H₂₅NO₄
• CAS-Nummer: 189442-87-3
• Molekulargewicht: 271.35
• MDL-Nummer: MFCD08689955
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24885188
• NACRES: NA.22

Eigenschaften

• Assay: 97%
• Brechungsindex: n20/D 1.4554
• Dichte: 1.0134 g/mL at 25 °C
• SMILES String: CCOC(=O)C1(C)CCN(CC1)C(=O)OC(C)(C)C
• InChI: 1S/C14H25NO4/c1-6-18-11(16)14(5)7-9-15(10-8-14)12(17)19-13(2,3)4/h6-10H2,1-5H3
• InChIKey: ZQZVWDXMUCTNRI-UHFFFAOYSA-N

Beschreibung

Anwendung

Reactant for synthesis of:

• Dipeptidyl peptidase-4 inhibitor ABT-279
• Building blocks for piperazine-based CCR5 antagonists

Replacement of the ester function with an amino group provides a key building block for piperazine-based CCR5 antagonists.

Sicherheitshinweise

• Piktogramme: GHS06,GHS05
• Signalwort: Danger
• H-Sätze: H301,H315,H318,H335
• P-Sätze: P261 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 3 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): >230.0 °F
• Flammpunkt (°C): > 110 °C
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter