660078

(R)-(−)-1-Cbz-3-Aminopyrrolidin

97%

• Synonym(e): (R)-1-Benzyloxycarbonyl-3-aminopyrrolidin
• Empirische Formel (Hill-System): C₁₂H₁₆N₂O₂
• CAS-Nummer: 122536-73-6
• Molekulargewicht: 220.27
• MDL-Nummer: MFCD05864624
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 24884456
• NACRES: NA.22

Eigenschaften

• Assay: 97%
• Brechungsindex: n20/D 1.548
• bp: 315 °C
• Dichte: 1.155 g/mL at 25 °C
• Funktionelle Gruppe: phenyl
• SMILES String: N[C@@H]1CCN(C1)C(=O)OCc2ccccc2
• InChI: 1S/C12H16N2O2/c13-11-6-7-14(8-11)12(15)16-9-10-4-2-1-3-5-10/h1-5,11H,6-9,13H2/t11-/m1/s1
• InChIKey: FPXJNSKAXZNWMQ-LLVKDONJSA-N

Beschreibung

Anwendung

(R)-(−)-1-Cbz-3-aminopyrrolidine can be used:

• In one of the key synthetic steps for the preparations of AZ82, a KIFC1-specific inhibitor for cancer therapy.
• As a key intermediate in the synthesis of N⁶-substituted adenosine analogs as potent A₁AR agonists.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H315,H319,H335
• P-Sätze: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): >230.0 °F - closed cup
• Flammpunkt (°C): > 110 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter