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Diethyl-(2-oxobutyl)phosphonat
96%
Synonym(e):
(2-Oxobutyl)phosphonic acid diethyl ester, Diethyl propanoylmethylphosphonate
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About This Item
Lineare Formel:
(C2H5O)2PCH2COCH2CH3
CAS-Nummer:
Molekulargewicht:
208.19
MDL-Nummer:
UNSPSC-Code:
12352108
PubChem Substanz-ID:
NACRES:
NA.22
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Assay
96%
Eignung der Reaktion
reaction type: C-C Bond Formation
Brechungsindex
n20/D 1.4360 (lit.)
Dichte
1.072 g/mL at 25 °C (lit.)
SMILES String
CCOP(=O)(CC(=O)CC)OCC
InChI
1S/C8H17O4P/c1-4-8(9)7-13(10,11-5-2)12-6-3/h4-7H2,1-3H3
InChIKey
GQBVFZDYDHGZPY-UHFFFAOYSA-N
Anwendung
Reactant for synthesis of:
- Oxa(bicyclo)octanone for use in preparing cycloheptane annulated furans
- Anatoxin-a and homoanatoxin via the Wittig reaction
- α-Methylene-β-amino ketones
- 2-Amino-5-phosphono- and 2-amino-4-(phosphonomethyl)thiophenes using the Gewald reaction
- Aliphatic musk odorants
- Oxoalkylphosphonates
Lagerklassenschlüssel
12 - Non Combustible Liquids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves
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Nina V Fuchs et al.
Stem cell research, 41, 101592-101592 (2019-11-08)
The Renpenning syndrome spectrum is a rare X-linked mental retardation syndrome characterized by intellectual disability, microcephaly, low stature, lean body and hypogonadism. Mutations in the polyglutamine tract binding protein 1 (PQBP1) locus are causative for disease. Here, we describe the
Katharina Hutter et al.
Molecular cell, 78(5), 876-889 (2020-06-06)
Many microRNAs (miRNAs) are generated from primary transcripts containing multiple clustered stem-loop structures that are thought to be recognized and cleaved by the Microprocessor complex as independent units. Here, we uncover an unexpected mode of processing of the bicistronic miR-15a-16-1
Seung Wook Yang et al.
Molecular cell, 77(6), 1206-1221 (2020-01-26)
Alternative polyadenylation (APA) contributes to transcriptome complexity by generating mRNA isoforms with varying 3' UTR lengths. APA leading to 3' UTR shortening (3' US) is a common feature of most cancer cells; however, the molecular mechanisms are not understood. Here
Vera Chesnokova et al.
Endocrinology, 160(6), 1439-1447 (2019-04-20)
DNA damage occurs as a result of environmental insults and aging and, if unrepaired, may lead to chromosomal instability and tumorigenesis. Because GH suppresses ataxia-telangiectasia mutated kinase phosphorylation, decreases DNA repair, and increases DNA damage accumulation, we elucidated whether GH
Penelope Kroustallaki et al.
Cell reports, 28(7), 1690-1702 (2019-08-15)
Telomerase biogenesis is a complex process where several steps remain poorly understood. Single-strand-selective uracil-DNA glycosylase (SMUG1) associates with the DKC1-containing H/ACA ribonucleoprotein complex, which is essential for telomerase biogenesis. Herein, we show that SMUG1 interacts with the telomeric RNA component
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