561037

3,4-Difluorphenylmagnesiumbromid -Lösung

0.5 M in THF

• Lineare Formel: F₂C₆H₃MgBr
• CAS-Nummer: 90897-92-0
• Molekulargewicht: 217.29
• MDL-Nummer: MFCD00672004
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 24879910
• NACRES: NA.22

Eigenschaften

• Eignung der Reaktion: reaction type: Grignard Reaction
• Konzentration: 0.5 M in THF
• bp: 65 °C
• Dichte: 0.965 g/mL at 25 °C
• Lagertemp.: 2-8°C
• SMILES String: Fc1ccc([Mg]Br)cc1F
• InChI: 1S/C6H3F2.BrH.Mg/c7-5-3-1-2-4-6(5)8;;/h1,3-4H;1H;/q;;+1/p-1
• InChIKey: WZHAVYGMKGPNFN-UHFFFAOYSA-M

Beschreibung

Anwendung

3,4-Difluorophenylmagnesium bromide can be used:

• To prepare 3,4-difluorophenylboronic acid, a key building block employed in the synthesis of norepinephrine transporter selective molecules.
• In the synthesis of trimethoxybenzophenone derived tubulin polymerization inhibitors.
• In one of the key synthetic steps for the preparation of diarylketoxime derivatives as potent MCH-1R antagonists.
• In the synthesis of biologically important hydroxybupropion analogs useful in smoking cessation.

Rechtliche Hinweise

Product of Rieke^® Metals, Inc.

Sicherheitshinweise

• Piktogramme: GHS02,GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H225,H302,H319,H335,H351
• P-Sätze: P210 - P280 - P301 + P312 + P330 - P305 + P351 + P338 - P370 + P378 - P403 + P235
• Gefahreneinstufungen: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Zusätzliche Gefahrenhinweise: EUH019
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 1.0 °F - closed cup
• Flammpunkt (°C): -17.2 °C - closed cup