549606

2′-Aminoacetanilid

98%

• Synonym(e): N-(2-Aminophenyl)acetamide, o-Aminoacetanilide
• Lineare Formel: CH₃CONHC₆H₄NH₂
• CAS-Nummer: 34801-09-7
• Molekulargewicht: 150.18
• MDL-Nummer: MFCD00210388
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24874710

Eigenschaften

• Assay: 98%
• mp (Schmelzpunkt): 133-137 °C (lit.)
• SMILES String: CC(=O)Nc1ccccc1N
• InChI: 1S/C8H10N2O/c1-6(11)10-8-5-3-2-4-7(8)9/h2-5H,9H2,1H3,(H,10,11)
• InChIKey: MPXAYYWSDIKNTP-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

2′-Aminoacetanilide (2-aminoacetanilide, o-aminoacetanilide) can be prepared by the catalytic hydrogenation of 2-nitroacetanilide using 10%Pd/C (palladium/carbon).

Anwendung

2′-Aminoacetanilide may be used in the preparation of:

• 2-Methylbenzimidazole.
• N-(2-(1,3-Dimethyl-2,4-dioxo-5-phenyl-3,4-dihydro-1H-pyrrolo[3,4-d]pyrimidin-6(2H)-yl)phenyl)-5-methylfuran-2-carboxamide, a potent cystic fibrosis transmembrane conductance regulator (CFTR) inhibitor.
• Azobenzothiazole dyes, N-[2-(6-nitrobenzothiazol-2-ylazo)phenyl]acetamide and N-[2-(benzothiazol-2-ylazo)phenyl]acetamide.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves