470708

Methyl-3-hydroxy-4-methoxybenzoat

98%

• Lineare Formel: HOC₆H₃(OCH₃)CO₂CH₃
• CAS-Nummer: 6702-50-7
• Molekulargewicht: 182.17
• MDL-Nummer: MFCD01321262
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24870673
• NACRES: NA.22

Eigenschaften

• Assay: 98%
• Form: solid
• mp (Schmelzpunkt): 64-67 °C (lit.)
• SMILES String: COC(=O)c1ccc(OC)c(O)c1
• InChI: 1S/C9H10O4/c1-12-8-4-3-6(5-7(8)10)9(11)13-2/h3-5,10H,1-2H3
• InChIKey: QXOXUEFXRSIYSW-UHFFFAOYSA-N

Beschreibung

Anwendung

Methyl 3-hydroxy-4-methoxybenzoate may be used as starting reagent in the novel synthesis of gefitinib. Synthesis involves the alkylation of starting material, followed by nitration, reduction, cyclization, chlorination and two successive amination reactions. It may be used as starting reagent in the synthesis of methyl 5-(benzo[d][1,3]dioxol-5-yl)-4-methoxy-2-nitrobenzoate.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves