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425311

Sigma-Aldrich

IR-780 Iodid

Dye content ≥95 %

Synonym(e):

2-[2-[2-Chlor-3-[(1,3-dihydro-3,3-dimethyl-1-propyl-2H-indol-2-yliden)ethyliden]-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-1-propylindolium-iodid

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1 G
CHF 215.00

CHF 215.00


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1 G
CHF 215.00

About This Item

Empirische Formel (Hill-System):
C36H44ClIN2
CAS-Nummer:
Molekulargewicht:
667.11
MDL-Nummer:
UNSPSC-Code:
12352103
PubChem Substanz-ID:
NACRES:
NA.23

CHF 215.00


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Form

solid

Qualitätsniveau

Zusammensetzung

Dye content, ≥95%

mp (Schmelzpunkt)

232-234 °C (lit.)

λmax

780 nm

SMILES String

[I-].CCCN1c2ccccc2C(C)(C)/C1=C\C=C3/CCCC(\C=C\C4=[N+](CCC)c5ccccc5C4(C)C)=C3Cl

InChI

1S/C36H44ClN2.HI/c1-7-24-38-30-18-11-9-16-28(30)35(3,4)32(38)22-20-26-14-13-15-27(34(26)37)21-23-33-36(5,6)29-17-10-12-19-31(29)39(33)25-8-2;/h9-12,16-23H,7-8,13-15,24-25H2,1-6H3;1H/q+1;/p-1

InChIKey

IRPKBYJYVJOQHQ-UHFFFAOYSA-M

Allgemeine Beschreibung

IR-780 iodide is a near-infrared lipophilic cation heptamethine fluorescent dye. It has a good fluorescent intensity and can be used as a photothermal therapy agent. It shows an optical absorption spectrum of 780 nm that makes it useful as a sonodynamic therapy agent for medical treatment.[1][2][3]

Anwendung

IR-780 based dyes can be potentially used in a biomedical application and drug delivery for tumor imaging and targeted therapy.[4][5]

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Kunden haben sich ebenfalls angesehen

IR-780 dye as a sonosensitizer for sonodynamic therapy of breast tumor
Li Y, et al.
Scientific Reports, 6(28), 25968-25968 (2016)
IR-780 dye for near-infrared fluorescence imaging in prostate cancer
Yi X, et al.
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research, 21(28), 511-511 (2015)
IR-780 dye loaded tumor targeting theranostic nanoparticles for NIR imaging and photothermal therapy
Yue C, et al.
Biomaterials, 34(28), 6853-6861 (2013)
Preferential accumulation of the near infrared heptamethine dye IR-780 in the mitochondria of drug-resistant lung cancer cells
Wang Y, et al.
Biomaterials, 35(13), 4116-4124 (2014)
Sentinel lymph node mapping by a near-infrared fluorescent heptamethine dye
Zhang C, et al.
Biomaterials, 31(7), 1911-1917 (2010)

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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