297771
4-Methylpyridazin
97%
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About This Item
Empfohlene Produkte
Assay
97%
Brechungsindex
n20/D 1.521 (lit.)
bp
98-100 °C/11 mmHg (lit.)
Dichte
1.06 g/mL at 25 °C (lit.)
SMILES String
Cc1ccnnc1
InChI
1S/C5H6N2/c1-5-2-3-6-7-4-5/h2-4H,1H3
InChIKey
AIKUBOPKWKZULG-UHFFFAOYSA-N
Allgemeine Beschreibung
Products of reaction of methyl iodide with 4-methylpyridazine has been investigated by NMR spectra. Solvent free oxidation of 4-methylpyridazine by acetyl peroxyborate, peracetic acid and hydrogen peroxide has been reported.
Anwendung
4-Methylpyridazine was used in the preparation of series of novel pyridazine derivatives structurally related to bipyridine cardiotonics.
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Zielorgane
Respiratory system
Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 3
Flammpunkt (°F)
222.8 °F - closed cup
Flammpunkt (°C)
106 °C - closed cup
Persönliche Schutzausrüstung
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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Investigation of the quaternisation products of 3-and 4-methylpyridazines by nuclear magnetic resonance spectroscopy.
Journal of the Chemical Society B: Physical Organic, 867-870 (1966)
Die Pharmazie, 44(9), 598-601 (1989-09-01)
Preparation of a series of novel pyridazine derivatives structurally related to bipyridine cardiotonics, starting from 4-methylpyridazine or 4-acetylpyridazine, respectively, is described. As observed with compounds 8, 11 and 16, an enhancement of in vitro cardiotonic activity is associated with the
Chemistry (Weinheim an der Bergstrasse, Germany), 14(8), 2340-2348 (2008-01-30)
Niacin (3-picolinic acid), which is extensively used as vitamin B3 in foodstuffs and as a cholesterol-lowering agent, along with other oxygenated products of the picolines, 4-methylquinoline, and a variety of pyrimidines and pyridazines, may be produced in a single-step, environmentally
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