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219746

Sigma-Aldrich

DL-Homocysteinsäure

97%

Synonym(e):

DL-2-Amino-4-sulfobuttersäure

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About This Item

Lineare Formel:
HO3SCH2CH2CH(NH2)CO2H
CAS-Nummer:
504-33-6
Molekulargewicht:
183.18
EG-Nummer:
207-991-0
MDL-Nummer:
MFCD00007536
UNSPSC-Code:
12352100
PubChem Substanz-ID:
24853141
NACRES:
NA.22

Assay

97%

Form

solid

mp (Schmelzpunkt)

273 °C (dec.) (lit.)

Löslichkeit

water: soluble 50 mg/mL, clear to slightly hazy, colorless to yellow

Funktionelle Gruppe

amine

SMILES String

NC(CCS(O)(=O)=O)C(O)=O

InChI

1S/C4H9NO5S/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H,8,9,10)

InChIKey

VBOQYPQEPHKASR-UHFFFAOYSA-N

Allgemeine Beschreibung

Complexes of DL-homocysteic acid with Na+, Cu2+, Zn2+ and Ni2+ has been synthesized. DL-Homocysteic acid induces oxidative stress in brain of immature rats.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Rhodamin B ≥95% (HPLC)

Sigma-Aldrich

R6626

Rhodamin B

Hui-Zhen Jia et al.
Guang pu xue yu guang pu fen xi = Guang pu, 27(7), 1291-1294 (2007-10-20)
The complexes of DL-homocysteic acid (DLH) with Na+, Cu2+, Zn2+ and Ni2+ were synthesized and elemental analyses were used to detect the compositions of these complexes. FTIR spectroscopy was employed to study these coordination structures. The results indicated that all
Glauber S F da Silva et al.
Frontiers in physiology, 8, 452-452 (2017-07-18)
Hydrogen Sulfide (H
Jaroslava Folbergrová et al.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 31(2), 123-130 (2012-12-15)
We have recently demonstrated the evidence of oxidative stress in brain of immature rats during seizures induced by DL-homocysteic acid (DL-HCA). The aim of the present study was to investigate the antioxidant defense mechanisms under these conditions. Seizures were induced
Tohru Hasegawa et al.
PloS one, 5(1), e8593-e8593 (2010-01-26)
Alzheimer's disease (AD) is an age-associated progressive neurodegenerative disorder with dementia, the exact pathogenic mechanisms of which remain unknown. We previously reported that homocysteic acid (HA) may be one of the pathological biomarkers in the brain with AD and that
Hari H Subramanian et al.
The Journal of comparative neurology, 521(13), 3083-3098 (2013-05-01)
The midbrain periaqueductal gray (PAG) is involved in many basic survival behaviors that affect respiration. We hypothesized that the PAG promotes these behaviors by changing the firing of preinspiratory (pre-I) neurons in the pre-Bötzinger complex, a cell group thought to
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