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115053

Sigma-Aldrich

2-(4-Nitrophenyl)-ethylbromid

98%

Synonym(e):

1-(2-Bromethyl)-4-nitrobenzol

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About This Item

Lineare Formel:
O2NC6H4CH2CH2Br
CAS-Nummer:
5339-26-4
Molekulargewicht:
230.06
Beilstein:
1909321
EG-Nummer:
226-271-7
MDL-Nummer:
MFCD00007386
UNSPSC-Code:
12352100
PubChem Substanz-ID:
24847197

Assay

98%

Form

solid

mp (Schmelzpunkt)

67-69 °C (lit.)

Funktionelle Gruppe

bromo
nitro

SMILES String

[O-][N+](=O)c1ccc(CCBr)cc1

InChI

1S/C8H8BrNO2/c9-6-5-7-1-3-8(4-2-7)10(11)12/h1-4H,5-6H2

InChIKey

NTURQZFFJDCTMZ-UHFFFAOYSA-N

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Allgemeine Beschreibung

4-nitrophenethyl bromide is an electrophile which accepts a lone pair of electrons from one of the nitrogen atoms in the polyazamacrocycle.

Anwendung

4-nitrophenethyl bromide is used a s a GST T1-1 substrate for identifying many kinetic parameters (Km, Kcat) for hGST T1-1 variants.

Biochem./physiol. Wirkung

4-Nitrophenethyl bromide is used as a marker in for the θ-class of glutathione S-transferases (GSTs). It activates the human θ-class glutathione transferase T1-1 enzyme.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
BCBX4289
BCBW7796
MKBQ0435V
09015BW
U15676

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Abeer Shokeer et al.
The Biochemical journal, 388(Pt 1), 387-392 (2005-02-03)
GST (glutathione transferase) T1-1 plays an important role in the biotransformation of halogenated alkanes, which are used in large quantities as solvents and occur as environmental pollutants. Many reactions that are catalysed by GST T1-1 qualify as detoxification processes, but
M F Lopez et al.
Biochimica et biophysica acta, 1205(1), 29-38 (1994-03-16)
A novel glutathione S-transferase (GST) was purified from broccoli (Brassica oleracea var. italica). Partial amino-acid sequencing indicated that the protein shared significant homology with several different plant GSTs from maize, silene, Dianthus, Nicotiana and Triticum, but little homology to yeast
Birute Surinenaite et al.
Biotechnology and applied biochemistry, 36(Pt 1), 47-55 (2002-08-01)
The lipase from Pseudomonas mendocina 3121-1 was found to be homogeneous with a molecular mass of 30 kDa by SDS/PAGE. It is composed of two identical subunits. A molecular mass of 62 kDa was determined by gel chromatography on a
Amalia Rodríguez et al.
Journal of colloid and interface science, 248(2), 455-461 (2005-11-18)
The reactions 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane + OH(-) and 2-(p-nitrophenyl)ethyl bromide + OH(-) were studied in tetradecyltrimethylamonium bromide, TTAB, and TTAB-pentanol micellar solutions. The influence of changes in the surfactant concentration as well as changes in the hydroxide ion concentration on the observed
H M V Udayantha et al.
Fish & shellfish immunology, 109, 62-70 (2020-12-22)
Glutathione S-transferases (GSTs) are important enzymes involved in phase II detoxification and function by conjugating with the thiol group of glutathione. In this study, we isolated an omega class GST from the big-belly seahorse (Hippocampus abdominalis; HaGSTO1) to study the
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