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Merck

THRB

thyroid hormone receptor, beta

Synonyme:
C-ERBA-2, C-ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(7068) Summary: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(21834) thyroid hormone receptor beta
  • Rat(24831) thyroid hormone receptor beta
  • Domestic Rabbit(100303763) thyroid hormone receptor, beta
  • chicken(396431) thyroid hormone receptor, beta
  • cow(788329) thyroid hormone receptor, beta
  • domestic cat(101084821) thyroid hormone receptor, beta
  • Horse(100051615) thyroid hormone receptor, beta
  • dog(403599) thyroid hormone receptor, beta
  • naked mole-rat(101719651) thyroid hormone receptor, beta
  • domestic guinea pig(100721125) thyroid hormone receptor, beta
  • Zebrafish(30607) thyroid hormone receptor beta

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
3,3′,5-Triiodo-L-thyronin (T3) -Lösung, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
L-Thyroxin (T4) -Lösung, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Levothyroxin, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Levothyroxinnatrium, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Liothyronin, United States Pharmacopeia (USP) Reference Standard,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
3,3′,5-Triiod-L-thyronin Natriumsalz, powder, BioReagent, suitable for cell culture,
Spezies
rat, human
3,3′,5-Triiod-L-thyronin, ≥95% (HPLC), powder,
Spezies
rat, human
3,3′,5-Triiod-L-thyronin Natriumsalz, γ-irradiated, powder, suitable for, suitable for cell culture,
Spezies
rat, human
3,3′,5-Triiodothyroessigsäure, ≥90%,
Spezies
rat, human
L-Thyroxin, ≥98% (HPLC),
Spezies
human, mouse, rat

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Thyroid Hormone Receptor β-1 Antibody, from rabbit, purified by affinity chromatography,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot
Anti-Thyroid Hormone Receptor β, N-Terminal antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry

western blot
Anti-THRB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
Anti-THRB antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
canine, human, mouse, rat
Anwendung
ELISA
western blot
Anti-phospho-TR-β1 (pSer142) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
3,3′,5-Triiod-L-thyronin Natriumsalz, powder, BioReagent, suitable for cell culture,
Spezies
rat, human
3,3′,5-Triiod-L-thyronin, ≥95% (HPLC), powder,
Spezies
rat, human
3,3′,5-Triiod-L-thyronin Natriumsalz, γ-irradiated, powder, suitable for, suitable for cell culture,
Spezies
rat, human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human THRB,
Spezies
human