Direkt zum Inhalt
Merck

ADRA2C

adrenoceptor alpha 2C

Synonyme:
ADRA2L2, ADRA2RL2, ADRARL2, ALPHA2CAR
Spezies:
Human ADRA2C (152), Mouse Adra2c (11553), Rat Adra2c (24175), domestic guinea pig Adra2c (100135477), domestic guinea pig Adra2c (101787589), cow ADRA2C (101902575), cow ADRA2C (407139), sheep ADRA2C (100170319), Zebrafish adra2c (266752), chicken ADRA2C (428799) ...Mehr
UniProtKB-ID:
P18825, P35369, Q9HB49
Gen-ID:
  • Human(152) Summary: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
  • Mouse(11553) adrenergic receptor, alpha 2c
  • Rat(24175) adrenoceptor alpha 2C
  • domestic guinea pig(100135477) adrenergic receptor, alpha 2c
  • domestic guinea pig(101787589) adrenoceptor alpha 2C
  • cow(101902575) adrenoceptor alpha 2C
  • cow(407139) alpha-2C adrenergic receptor
  • sheep(100170319) adrenoceptor alpha 2C
  • Zebrafish(266752) adrenergic, alpha-2C-, receptor
  • chicken(428799) adrenergic, alpha-2C-, receptor
  • dog(488793) adrenoceptor alpha 2C
  • domestic cat(101087990) adrenoceptor alpha 2C
  • domestic cat(100529244) adrenoceptor alpha 2C

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
C7897
Clonidin -hydrochlorid, solid,
Spezies
human
X1251
Xylazin -hydrochlorid, ≥99.0% (HPLC),
Spezies
human
857416
(−)-3-(3,4-Dihydroxyphenyl)-2-methyl-L-alanin Sesquihydrat, 99%,
Spezies
human
1426002
Methyldopa, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
G110
Guanabenz -acetat (Salz), powder,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Y3125
Yohimbin -hydrochlorid, ≥98% (HPLC), powder,
Spezies
human
I6138
Idazoxan hydrochloride, ,
Spezies
human
R9525
RX 821002 hydrochloride, solid, ≥98% (HPLC),
Spezies
human
U104
UK 14,304, ,
Spezies
human
M-128
Mirtazapine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
SAB5201006
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Apc antibody produced in mouse, clone S330A-80, purified immunoglobulin,
Speziesreaktivität
human, mouse
Anwendung
immunocytochemistry
western blot
SAB4500566
Anti-Adrenergic Receptor α-2C antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
western blot
HPA057688
Anti-ADRA2C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
SAB5200997
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Atto 390 antibody produced in mouse, clone S330A-80, purified immunoglobulin,
Speziesreaktivität
human, mouse
Anwendung
immunocytochemistry
western blot
SAB5200998
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Atto 488 antibody produced in mouse, clone S330A-80, purified immunoglobulin,
Speziesreaktivität
human, mouse
Anwendung
immunocytochemistry
western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
M2525
Mianserin -hydrochlorid, ,
Spezies
human
A7127
Agmatin -sulfat (Salz), ≥97%, powder,
Spezies
human

Small Molecule - Mixed Agonist/Antagonist

Produktnummer
Beschreibung
Spezies
U104
UK 14,304, ,
Spezies
human
A7257
(−)-Norepinephrin, ≥98%, crystalline,
Spezies
human, rat
H1512
Haloperidol, powder,
Spezies
human, rat
C6305
Clozapin, ,
Spezies
human, rat

esiRNA

Produktnummer
Beschreibung
Spezies
EMU033071
MISSION® esiRNA, targeting mouse Adra2c,
Spezies
mouse