S7920

Sodium fluoride

BioXtra, ≥99%

• Synonyme(s) : NaF, Natrium fluoride, Sodium monoflouride
• Formule linéaire : NaF
• Numéro CAS: 7681-49-4
• Poids moléculaire : 41.99
• Numéro CE : 231-667-8
• Numéro MDL: MFCD00003524
• Code UNSPSC : 12352302
• ID de substance PubChem : 24899770
• Nomenclature NACRES : NA.25

Propriétés

• Pression de vapeur: 1.4 mmHg ( 0 °C)
• Niveau de qualité: 200
• Gamme de produits: BioXtra
• Pureté: ≥99%
• Impuretés: ≤0.0005% Phosphorus (P); ≤0.1% Insoluble matter
• Pf: 993 °C (lit.)
• Solubilité: H₂O: 1 M, clear, colorless
• Traces d'anions: chloride (Cl^-): ≤0.005%; sulfate (SO₄^2-): ≤0.03%
• Traces de cations: Al: ≤0.001%; Ca: ≤0.0005%; Cu: ≤0.0005%; Fe: ≤0.003%; K: ≤0.02%; Mg: ≤0.0005%; NH₄⁺: ≤0.1%; Pb: ≤0.001%; Zn: ≤0.0005%
• Chaîne SMILES: [F-].[Na+]
• InChI: 1S/FH.Na/h1H;/q;+1/p-1
• Clé InChI: PUZPDOWCWNUUKD-UHFFFAOYSA-M

Description

Application

Sodium fluoride has been used:

• as a source of fluoride ions, to analyse its impact on spermatogenesis and capacitation in vitro
• as an additive in the extraction buffer for the isolation of nuclei, cytoplasmic and nuclear proteins
• as a component of lysis buffer for the lysis of human ovarian adenocarcinoma OVCAR3 cells

Actions biochimiques/physiologiques

Sodium fluoride (NaF) prevents dental caries, by catalysing the diffusion of calcium and phosphate and remineralizes the lesions. Fluoride affects spermatogenesis and capacitation process in the female reproductive tract. Fluoride induces oxidative stress, DNA damage in ovary ultimately affects the development of oocytes. Fluoride supplementation enhances bone mineral density. 18F-NaF is a radiotracer used in positron emission tomography (PET) to identify atherosclerotic lesions and other cardiac plaques.

Autres remarques

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Informations sur la sécurité

• Pictogrammes: GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H301,H315,H319
• Conseils de prudence: P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Classification des risques: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Risques supp: EUH032
• Code de la classe de stockage: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges