BP021

Ampicilline trihydrate

British Pharmacopoeia (BP) Reference Standard

• Synonyme(s) : D-(−)-α-aminobenzylpénicilline
• Formule empirique (notation de Hill) : C₁₆H₁₉N₃O₄S · 3H₂O
• Numéro CAS: 7177-48-2
• Poids moléculaire : 403.45
• EC Number: 200-709-7
• UNSPSC Code: 41116107
• NACRES: NA.24
• Beilstein/REAXYS Number: 5399534
• MDL number: MFCD00072036

Propriétés

• grade: pharmaceutical primary standard
• API family: ampicillin
• form: solid
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: BP
• mp: 198-200 °C (dec.) (lit.)
• application(s): pharmaceutical; pharmaceutical small molecule
• format: neat
• storage temp.: −20°C (−15°C to −25°C)
• SMILES string: O.O.O.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(O)=O
• InChI: 1S/C16H19N3O4S.3H2O/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;;;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);3*1H2/t9-,10-,11+,14-;;;/m1.../s1
• InChI key: RXDALBZNGVATNY-CWLIKTDRSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ampicillin trihydrate BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Co-fluampicil Oral Suspension

Co-fluampicil Capsules

Ticarcillin and Clavulanic Acid Infusion

Ampicillin Oral Suspension

Ampicillin Injection

Ampicillin Capsules

Amoxicillin Veterinary Oral Powder

Amoxicillin Oily Injections

Amoxicillin Injection

Amoxicillin Oral Suspension

Amoxicillin Capsules

Amoxicillin Tablets

Biochem/physiol Actions

Un antibiotique β-lactamine avec groupement amine sur une chaîne latérale fixée à la structure de la pénicilline. Dérivé de la pénicilline qui inhibe la synthèse de la paroi bactérienne (réticulation des peptidoglycanes) en inactivant les transpeptidases situées sur la face interne de la membrane bactérienne. Bactéricide uniquement sur Escherichia coli en développement. Mode de résistance : clivage de l′anneau β-lactame de l′ampicilline par la β-lactamase. Spectre antimicrobien : bactéries Gram-négatif et Gram-positif.

Packaging

Unit quantity: 500 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Other Notes

Sales restrictions may apply.

Informations sur la sécurité

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H315,H317,H319,H334,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable