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Key Documents

B1215000

2,6-Di-tert-butyl-4-methylphenol

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Butylhydroxytoluène, Hydroxytoluène butylé

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About This Item

Formule linéaire :
[(CH3)3C]2C6H2(CH3)OH
Numéro CAS:
Poids moléculaire :
220.35
Numéro Beilstein :
1911640
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Densité de vapeur

7.6 (vs air)

Pression de vapeur

<0.01 mmHg ( 20 °C)

Température d'inflammation spontanée

878 °F

Fabricant/nom de marque

EDQM

Point d'ébullition

265 °C (lit.)

Pf

69-73 °C (lit.)

Application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C

InChI

1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3

Clé InChI

NLZUEZXRPGMBCV-UHFFFAOYSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application


  • Multicomponent analysis of fat- and water-soluble vitamins and auxiliary substances in multivitamin preparations by qNMR.: This study utilizes Butylhydroxytoluene (BHT) as an auxiliary substance for its antioxidant properties in multivitamin preparations. The research demonstrates the effectiveness of BHT in maintaining the oxidative stability of vitamins, ensuring their longevity and efficacy in pharmaceutical applications (Eiff et al., 2015).

  • Investigation of the stabilizing effects of antioxidants and benzophenone-3 on desonide photostability.: The study explores the use of BHT as an antioxidant to enhance the photostability of desonide. Findings indicate that BHT significantly improves the stability of the compound under light exposure, making it a valuable preservative in pharmaceutical and biotechnological formulations (Rosa et al., 2014).


  • Understanding the molecular aspects of tetrahydrocannabinol and cannabidiol as antioxidants.: This research highlights BHT′s role as a comparative antioxidant in studying the properties of cannabinoids. BHT′s well-documented antioxidant mechanisms provide a benchmark for evaluating the efficacy of other compounds in oxidative stress research (Borges et al., 2013).


  • Kinetic study of the quenching reaction of singlet oxygen by common synthetic antioxidants.: The kinetic analysis of BHT′s ability to quench singlet oxygen demonstrates its superior antioxidant capabilities compared to other synthetic antioxidants. This property is crucial for developing pharmaceutical formulations that require high oxidative stability (Kim et al., 2009).



Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Pictogrammes

Environment

Mention d'avertissement

Warning

Mentions de danger

Conseils de prudence

Classification des risques

Aquatic Acute 1 - Aquatic Chronic 1

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

260.6 °F - open cup

Point d'éclair (°C)

127 °C - open cup


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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Mateusz Maciejczyk et al.
Nutrients, 10(10) (2018-10-20)
A high-sucrose diet (HSD) is widely known for its cariogenic effects and promotion of obesity, insulin resistance, type 2 diabetes, and cancer. However, the impact of the HSD diet on the salivary gland function as well as the level of
Urszula Kołodziej et al.
Archives of oral biology, 84, 6-12 (2017-09-20)
Chronic high protein intake leads to an increase in reactive oxygen species (ROS) generation. However, there is no data on the impact of high-protein diet on the antioxidant barrier, oxidative stress and secretory function in the salivary glands of healthy
Priscila Sutto-Ortiz et al.
PeerJ, 5, e3524-e3524 (2017-07-12)
Novel microbial phospholipases A (PLAs) can be found in actinomycetes which have been poorly explored as producers of this activity. To investigate microbial PLA production, efficient methods are necessary such as high-throughput screening (HTS) assays for direct search of PLAs in
Ana Claudia Hertel Pereira et al.
Pharmaceutical biology, 55(1), 472-480 (2016-12-13)
The resin from the trunk wood of Virola oleifera (Schott) A. C. Smith (Myristicaceae) is used in folk medicine to hasten wound repair and to treat pain and inflammatory conditions, and our previous report indicated the anti-oxidative properties in other
Graziana Difonzo et al.
Foods (Basel, Switzerland), 8(4) (2019-04-26)
The shelf-life extension implicates the reduction of food waste. Plant polyphenols can have a crucial role in the shelf-life extension of foods. Olive leaf extract (OLE) is rich in phenolic compounds such as oleuropein, which is well-known for its antioxidant

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