ATPDS-RO

Adenosine 5′-triphosphate disodium salt trihydrate

=99%, pkg of 1 g (10519979001), pkg of 5 g (10519987001)

• Synonyme(s) : ATP
• Formule empirique (notation de Hill): C₁₀H₂₀N₅Na₂O₁₆P₃
• Numéro CAS: 51963-61-2
• Poids moléculaire : 605.19
• Numéro MDL: MFCD00150754
• Code UNSPSC : 41106305
• ID de substance PubChem : 329773088

Propriétés

• Niveau de qualité: 100
• Description: Disodium salt
• Pureté: 99%
• Forme: crystals
• Poids mol.: 507.2 (ATP); M_r 551.14 (ATP-Na2)
• Conditionnement: pkg of 1 g (10519979001); pkg of 5 g (10519987001)
• Fabricant/nom de marque: Roche
• Température de stockage: 2-8°C
• Chaîne SMILES: O.O.O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H16N5O13P3.2Na.3H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;3*1H2/q;2*+1;;;/p-2/t4-,6-,7-,10-;;;;;/m1...../s1
• Clé InChI: MWEQTWJABOLLOS-AZGWGOJFSA-L

Description

Description générale

The special quality of ATP contains highly purified Adenosine-5′-triphosphate in crystal form.

Application

Adenosine 5′-triphosphate disodium salt trihydrate has been used:

• in analyzing the ATP turnover cycle of microtubule motors
• for activating the NLR family pyrin domain containing 3 (NLRP3) inflammasome to perform in vitro stimulation of bone marrow-derived dendritic cells (BMDCs)
• for in vitro ubiquitination

It is also suitable for the luminometric determination of luciferase (Luc) activity in cell extracts.

Actions biochimiques/physiologiques

Adenosine 5′-triphosphate (ATP) is a key energy currency, with high phosphate transfer potential, in all living organisms. ATP participates in several biological processes such as membrane transport, muscle contraction and synthesis, and degradation of biological molecules. It serves as an intracellular and extracellular signaling molecule in certain cellular processes such as cell motility, organ development, neurotransmission, and insulin secretion. Adenosine 5′-triphosphate (ATP) acts as a substrate for proteins of the kinesin superfamily.

Notes préparatoires

Storage conditions (working solution): The reconstituted aqueous solution is stable at 2 to 8 °C for one week.

Autres remarques

For life science research only. Not for use in diagnostic procedures.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable