G11950

Guanine

98%

• Synonyme(s) : 2-Amino-1,7-dihydro-6H-purin-6-one, 2-Amino-6-hydroxypurine, 2-Aminohypoxanthine
• Formule empirique (notation de Hill): C₅H₅N₅O
• Numéro CAS: 73-40-5
• Poids moléculaire : 151.13
• Numéro Beilstein : 9680
• Numéro CE : 200-799-8
• Numéro MDL: MFCD00071533
• Code UNSPSC : 12352005
• ID de substance PubChem : 24895050
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 200
• Pureté: 98%
• Pf: >300 °C (lit.)
• Solubilité: hydrochloric acid: soluble 5 M, clear to slightly hazy, colorless to faintly yellow-green
• Chaîne SMILES: NC1=Nc2[nH]cnc2C(=O)N1
• InChI: 1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
• Clé InChI: UYTPUPDQBNUYGX-UHFFFAOYSA-N

Description

Description générale

Adenine, cytosine, thymine and guanine are the four main nucleobases found in nucleic acids DNA and RNA. Guanine is a purine derivative. It is reported to assemble into square-planar groups that resemble macrocycles, in which the bases interact via hydrogen bonds. In DNA and RNA, stretches of guanine bases are reported to form stable four stranded helices in the presence of sodium or potassium ions. The electrochemical oxidation of guanine has been studied in aqueous media at various carbon electrodes. It reacts with peroxynitrite under physiological conditions to afford 8-nitroguanine.

Application

Guanine is suitable reagent used to investigate the mechanism of electrochemical oxidation of guanine and adenine using a glassy carbon microelectrode and cyclic and differential pulse voltammetry. It may be used in the preparation of mixed-sequence peptide nucleic acid (PNA) monomers.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves