E6635

Acide éthylènediaminetétraacétique disodium salt dihydrate

Sigma Grade, suitable for plant cell culture, 98.5-101.5%

• Synonyme(s) : EDTA disodium salt, EDTA-Na₂, Edétate disodium salt dihydrate, Sequestrene Na₂, Édathamil, Éthylènediaminetétraacétate disodique dihydrate
• Formule empirique (notation de Hill) : C₁₀H₁₄N₂Na₂O₈ · 2H₂O
• Numéro CAS: 6381-92-6
• Poids moléculaire : 372.24
• Beilstein: 3900609
• Numéro CE : 205-358-3
• Code UNSPSC : 12352107
• ID de substance PubChem : 24894632
• Nomenclature NACRES : NA.77

Propriétés

• Qualité: Sigma Grade
• Niveau de qualité: 200
• Essai: 98.5-101.5%
• Forme: powder
• Pertinence de la réaction: reagent type: chelator
• Technique(s): cell culture | plant: suitable
• Pf: 248 °C (dec.) (lit.)
• Solubilité: H₂O: soluble, clear, colorless
• Chaîne SMILES: O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O
• InChI: 1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2
• Clé InChI: OVBJJZOQPCKUOR-UHFFFAOYSA-L

Description

Description générale

Ethylenediaminetetraacetic acid (EDTA) is an aminopolycarboxylic acid and a hexadentate ligand. It chelates with metal ions, especially with cations to form an octahedral complex.[1] Ethylenediaminetetraacetic acid disodium salt (EDTA) is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia. It chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests.[2] It enhances the antibacterial activity of lysozyme.[3] EDTA used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease.[4] EDTA chelation therapy may also protect from oxidative damage during blood and lipid peroxidation in liver fibrosis. [5]

Application

Chélateur de cations divalents. Inhibe les enzymes dont l′activité exige des cations divalents, comme les métalloprotéinases.

Ethylenediaminetetraacetic acid disodium salt dihydrate has been in seed germination trials of plant species[6] and in protein extraction from Moss, Physcomitrella paten.[7] It has also been used in lysis and vacuole buffer for the isolation of vacuoles from Petunia petals.[8]

Informations sur la sécurité

• Pictogrammes: GHS08,GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H332,H373
• Conseils de prudence: P260 - P271 - P304 + P340 + P312 - P314 - P501
• Classification des risques: Acute Tox. 4 Inhalation - STOT RE 2 Inhalation
• Organes cibles: Respiratory Tract
• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)