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Key Documents

30552

Supelco

Monensin methyl ester

Selectophore, ≥97.0% (TLC)

Synonyme(s) :

Methyl monensin

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About This Item

Formule empirique (notation de Hill):
C37H64O11
Numéro CAS:
Poids moléculaire :
684.90
Numéro Beilstein :
3641733
Code UNSPSC :
26111700
Nomenclature NACRES :
NB.61

Qualité

for ion-selective electrodes

Niveau de qualité

Gamme de produits

Selectophore

Pureté

≥97.0% (TLC)

Température de stockage

2-8°C

Chaîne SMILES 

CC[C@]1(CCC(O1)[C@]2(C)CC[C@]3(C[C@H](O)[C@@H](C)C(O3)[C@@H](C)[C@@H](OC)[C@H](C)C(=O)OC)O2)C4OC(C[C@@H]4C)C5O[C@@](O)(CO)[C@H](C)C[C@@H]5C

InChI

1S/C37H64O11/c1-11-35(32-21(3)17-27(44-32)29-20(2)16-22(4)37(41,19-38)47-29)13-12-28(45-35)34(8)14-15-36(48-34)18-26(39)23(5)31(46-36)24(6)30(42-9)25(7)33(40)43-10/h20-32,38-39,41H,11-19H2,1-10H3/t20-,21+,22+,23+,24+,25+,26-,27-,28+,29-,30-,31-,32-,34+,35-,36+,37-/m0/s1

Clé InChI

PFRZSHIENRKVSE-RJTHVKINSA-N

Description générale

Monensin, is an antibiotic produced by Streptomyces cinnamonensis. It is a naturally occurring ionophore. It has an acyclic polyether sequence and a terminal carboxylic acid moiety. It has the ability to effectively carry protons and cations through the cell membrane, hence it adequately harbours Na+ into a characteristic pseudoactivity, thereby effectively transporting it across a bio-membrane. It also forms stable complexes with k+, Rb+ and Ag+; hence it can be chemically modified to form cation-binding sites, thereby attaining transport functionalities.
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Application


  • The selectivity of membrane ion-selective electrodes: This research explores the use of temperature variations to adjust the selectivity of ion-selective electrodes, utilizing Monensin methyl ester as a key component for sodium ion detection (Zahran et al., 2010).

  • Spectroscopic and semiempirical studies of a proton channel formed by the methyl ester of monensin A.: This paper presents a detailed analysis of the proton channel properties of Monensin methyl ester through spectroscopic and computational methods, highlighting its potential in analytical chemistry applications (Huczyński et al., 2006).

  • Ion chromatography detector based on solid-state ion-selective electrode array.: The development of an ion chromatography detector employing solid-state ion-selective electrodes, with Monensin methyl ester playing a crucial role in sodium ion detection, is detailed in this study (Lee et al., 2000).

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Informations légales

Selectophore is a trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

Skull and crossbones

Mention d'avertissement

Danger

Mentions de danger

Conseils de prudence

Classification des risques

Acute Tox. 3 Oral

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Consulter la Bibliothèque de documents

Adam Huczyñski et al.
The journal of physical chemistry. B, 110(31), 15615-15623 (2006-08-04)
Monensin A is an ionophore able to carry protons and cations through the cell membrane. Its methyl ester (MON1) and its hydrates have been studied in acetonitrile, and its deuterated analogue by Fourier transform infrared (FTIR) and (1)H and (13)C
José N Sousa et al.
European journal of mass spectrometry (Chichester, England), 13(3), 191-198 (2007-09-21)
This paper reports the first comparative study of the gas-phase fragmentation chemistry of monensin in negative ion mode electrospray and nanoelectrospray tandem mass spectrometry. The fragmentation was observed to occur at lower energies in nanoelectrospray than electrospray. The major product
Biosynthesis of monensin.
Day LE
Antimicrobial Agents and Chemotherapy, 4 (4), 410-414 (1973)
Spectroscopic and semiempirical studies of a proton channel formed by the methyl ester of monensin A.
Huczynski A
The Journal of Physical Chemistry B, 110 (31), 15615-15623 (2006)
[Monensin, an electrically charged carboxyl ionophor, and its neutral methylester as ion active components for Na+ selective disk electrodes].
J G Schindler et al.
Biomedizinische Technik. Biomedical engineering, 32(1-2), 22-24 (1987-01-01)

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