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C-045

Supelco

Cannabidiol solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Synonyme(s) :

CBD

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About This Item

Formule empirique (notation de Hill):
C21H30O2
Numéro CAS:
13956-29-1
Poids moléculaire :
314.46
Numéro CE :
200-659-6
Numéro MDL:
MFCD00869597
Code UNSPSC :
41116107
ID de substance PubChem :
329774791
Nomenclature NACRES :
NA.24

Qualité

certified reference material

Niveau de qualité

300

Forme

liquid

Caractéristiques

SNAP-N-SPIKE®, SNAP-N-SHOOT®

Conditionnement

ampule of 1 mL

Fabricant/nom de marque

Cerilliant®

Concentration

1.0 mg/mL in methanol

Technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Application(s)

cannabis testing
cannabis testing

Format

single component solution

Température de stockage

−20°C

Chaîne SMILES 

CCCCCc1cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c(O)c1

InChI

1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18+/m0/s1

Clé InChI

QHMBSVQNZZTUGM-ZWKOTPCHSA-N

Informations sur le gène

human ... CNR1(1268)

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Catégories apparentées

Description générale

The Certified Spiking Solution® is suitable for cannabidiol testing by HPLC, GC/MS or LC-MS/MS methods in forensic analysis, clinical toxicology, urine drug testing, and Cannabis potency or impurity profiling testing applications.

Cannabidiol (CBD) is one of the important cannabinoids found in plants of the Cannabaceae family known for its non-psychoactive properties. It forms upon the decarboxylation of its precursor cannabidiolic acid in the presence of light or heat. It shows various therapeutic properties, such as antioxidative, anti-inflammatory, antimicrobial, neuroprotective, anxiolytic, and anticonvulsant.

Application

The Certified Reference Material (CRM) in solution can also be used as follows:
  • Determination of four cannabinoids from an oil matrix using reversed-phase high-performance liquid chromatography (RP-HPLC) combined with a diode array detector (DAD)
  • Development and validation of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) based technique to measure cannabidiol, ∆9-tetrahydrocannabinol, and its metabolites in whole blood samples obtained from rats administered a high dose of cannabidiol
  • Simultaneous determination of cannabidiol and tetrahydrocannabinol in different hemp oil-containing products using isocratic RP-HPLC coupled with UV detection
  • Multi-analysis of hair samples for Δ9-tetrahydrocannabinol, cannabinol, and cannabidiol by liquid-liquid extraction (LLE) followed by gas chromatography-mass spectrometry based quantification
  • Ultrasound-assisted extraction of cannabidiol from three different commercial topical products followed by GC-MS based determination

Caractéristiques et avantages

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

C-046

Cannabinol solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

C-084

Cannabidiol-D3 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

C-115

Cannabinol-D3 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-003

(−)-Δ9-THC-D3 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-005

(−)-trans-Δ9-THC solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-011

(−)-Δ9-THC-D3 solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-032

(−)-Δ8-THC solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-033

exo-THC solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-047

(±)-Δ9-THC solution, 100 μg/mL in heptane, ampule of 1 mL, Cerilliant®

C-150

Cannabichromenic Acid (CBCA) solution, 1.0 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

C-153

Cannabinolic Acid (CBNA) solution, 1.0 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

T-111

Tetrahydrocannabivarinic acid (THCVA) solution, 1.0 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

C-171

Cannabicyclolic Acid (CBLA) solution, 0.5 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

C-180

7-Hydroxy cannabidiol (7-OH-CBD) solution, 1 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

C-217

Hemp Compliance Mix solution, certified reference material, ampule of 1 mL, Cerilliant®

C-219

Cannabinoid Mixture (Neutrals) - 8 Component solution, 500 μg/mL in methanol (each analyte), certified reference material, ampule of 1 mL, Cerilliant®

T-151

THC-O-Acetate solution, 1 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

C-181

7-Carboxy cannabidiol (7-COOH-CBD) solution, 1 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

C-220

Cannabinoid Mixture - 3 Component solution, 1 mg/mL in methanol ((each analyte)), certified reference material, ampule of 1 mL, Cerilliant®

C-218

Cannabinoid Mixture (Acids) - 6 Component solution, 500 μg/mL (1% DIPEA and 0.05% Ascorbic acid in Acetonitrile,each analyte), certified reference material, ampule of 1 mL, Cerilliant®

C-223

7-Hydroxy cannabidiol-D3 (7-OH-CBD-D3) solution, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

C-224

7-Carboxy cannabidiol-D3 (7-COOH-CBD-D3) solution, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

T-112

11-Nor-9-carboxy-delta9-THCV solution, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

C-244

Cannabichromenic Acid (CBCA) solution, 1 mg/mL (1% DIPEA and 0.05% Ascorbic acid in Acetonitrile), certified reference material, ampule of 1 mL, Cerilliant®

C-240

Cannabidiphorol (CBDP) solution, 1 mg/mL (1% DIPEA and 0.05% Ascorbic Acid in Acetonitrile), certified reference material, ampule of 1 mL, Cerilliant®

C-254

6-Hydroxy cannabidiol (6-OH-CBD) solution, 1 mg/mL (Degassed Acetonitrile), certified reference material, ampule of 1 mL, Cerilliant®

C-228

Cannabidiol Hydroxyquinone (HU-331), certified reference material, vial of 5 mg, Cerilliant®

C-246

Cannabielsoin (CBE) solution, 1 mg/mL (Degassed Methanol), certified reference material, ampule of 1 mL, Cerilliant®

H-158

HU-308 solution, 1 mg/mL (Degassed Methanol), certified reference material, ampule of 1 mL, Cerilliant®

C-264

(±)-Cannabicyclolic Acid (CBLA) solution, 0.5 mg/mL (0.1% DIPEA, 0.05 Ascorbic Acid in Acetonitrile), certified reference material, ampule of 1 mL, Cerilliant®

T-182

THC-O-Acetate solution, 1 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

C-255

6-Hydroxy cannabidiol-D3 (6-OH-CBD-D3) solution, 100 μg/mL (Degassed Acetonitrile), certified reference material, ampule of 1 mL, Cerilliant®

C-238

Cannabidiol-O-beta-D-glucuronide sodium salt solution, 100 μg/mL in methanol (as free carboxylate), certified reference material, ampule of 1 mL, Cerilliant®

Pictogrammes

FlameSkull and crossbonesHealth hazard
GHS02,GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organes cibles

Eyes,Central nervous system

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

49.5 °F - closed cup

Point d'éclair (°C)

9.7 °C - closed cup

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Cannabidiolic acid analytical standard

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39961

Cannabidiolic acid

Raymond J M Niesink et al.
Addiction (Abingdon, England), 110(12), 1941-1950 (2015-08-04)
Between 2000 and 2005 the average percentage of Δ(9) -tetrahydrocannabinol (THC) in marijuana as sold in Dutch coffeeshops has increased substantially; the potency of domestic products (Nederwiet and Nederhasj) has particularly increased. In contrast with imported marijuana, Nederwiet hardly contained
R B Laprairie et al.
British journal of pharmacology, 172(20), 4790-4805 (2015-07-29)
Cannabidiol has been reported to act as an antagonist at cannabinoid CB1 receptors. We hypothesized that cannabidiol would inhibit cannabinoid agonist activity through negative allosteric modulation of CB1 receptors. Internalization of CB1 receptors, arrestin2 recruitment, and PLCβ3 and ERK1/2 phosphorylation
Paola Massi et al.
British journal of clinical pharmacology, 75(2), 303-312 (2012-04-18)
Over the past years, several lines of evidence support an antitumourigenic effect of cannabinoids including Δ(9)-tetrahydrocannabinol (Δ(9)-THC), synthetic agonists, endocannabinoids and endocannabinoid transport or degradation inhibitors. Indeed, cannabinoids possess anti-proliferative and pro-apoptotic effects and they are known to interfere with
Raphael Mechoulam et al.
Chemistry & biodiversity, 4(8), 1678-1692 (2007-08-23)
The aim of this review is to present some of the recent publications on cannabidiol (CBD; 2), a major non-psychoactive constituent of Cannabis, and to give a general overview. Special emphasis is laid on biochemical and pharmacological advances, and on
R Martin-Santos et al.
Current pharmaceutical design, 18(32), 4966-4979 (2012-06-22)
Animal and humans studies suggest that the two main constituents of cannabis sativa, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) have quite different acute effects. However, to date the two compounds have largely been studied separately. To evaluate and compare the acute
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