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A2646

Sigma-Aldrich

D-Arginine

≥98% (TLC), suitable for ligand binding assays

Synonyme(s) :

(R)-2-Amino-5-guanidinopentanoic acid

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About This Item

Formule linéaire :
H2NC(=NH)NH(CH2)3CH(NH2)CO2H
Numéro CAS:
157-06-2
Poids moléculaire :
174.20
Numéro Beilstein :
1725412
Numéro CE :
205-866-5
Numéro MDL:
MFCD00063116
Code UNSPSC :
12352209
eCl@ss :
32160406
ID de substance PubChem :
24890684
Nomenclature NACRES :
NA.32

product name

D-Arginine, ≥98% (TLC)

Pureté

≥98% (TLC)

Forme

powder

Technique(s)

ligand binding assay: suitable

Couleur

white to off-white

Pf

226 °C (dec.) (lit.)

Application(s)

peptide synthesis

Chaîne SMILES 

N[C@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m1/s1

Clé InChI

ODKSFYDXXFIFQN-SCSAIBSYSA-N

Informations sur le gène

rat ... Ppm1a(24666)

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Catégories apparentées

Description générale

Arginine (Arg) is a dibasic amino acid and exists as two enantiomers: D-Arg and L-Arg. D-Arg is a cationic endogenous amino acid and is found in the central nervous system.

Application

D-Arginine has been used:
  • as an organic substrate to study the metabolic versatility of freshwater sedimentary archaea feeding on different organic carbon sources
  • to study its role in the inhibition of Pseudorabies virus (PRV) plaque formation by arginase
  • as a reference standard for chromatographic separation

Actions biochimiques/physiologiques

D-Arginine is a semi-essential amino acid that maintains cell death in the central nervous system (CNS). It may possess neuroprotective actions against glucocorticoids induced neurotoxicity in the CNS.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Certificats d'analyse (COA)

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M Griselda Canteros
Drug discovery today, 19(5), 627-636 (2013-11-21)
In humans, as in other mammals, endogenous glucocorticoids (GCs) are essential for adapting to physiological life stress. They are also crucial for the healthy development of the fetus. However, when the physiological concentrations of GCs increase over a long period
Federica Lazzari et al.
Polymers, 12(4) (2020-04-17)
D- and L-arginine-based polyamidoamino acids, called D- and L-ARGO7, retain the chirality and acid/base properties of the parent -amino acids and show pH-dependent self-structuring in water. The ability of the ARGO7 chiral isomers to selectively interact with chiral biomolecules and/or
Bridget E Fomenky et al.
Scientific reports, 8(1), 14147-14147 (2018-09-22)
This study investigated the effect of supplementing the diet of calves with two direct fed microbials (DFMs) (Saccharomyces cerevisiae boulardii CNCM I-1079 (SCB) and Lactobacillus acidophilus BT1386 (LA)), and an antibiotic growth promoter (ATB). Thirty-two dairy calves were fed a
Hsien-Chi Wang et al.
Biochemical and biophysical research communications, 334(2), 631-637 (2005-07-13)
Pseudorabies virus (PRV) is a member of Alphahepesviruses; it is an enveloped virus with a double-stranded DNA genome. Polyamines (such as spermine and spermidine) are ubiquitous in animal cells and participate in cellular proliferation and differentiation. Previous results of our
Xiaobo Zhou et al.
Experimental cell research, 359(1), 195-204 (2017-07-29)
Preeclampsia(PE) is a pregnancy complication that is diagnosed by the new onset of hypertension and proteinuria. The etiology of PE remains unclear; however, growing evidence indicates that mitochondrial impairment contributes to the pathogenesis. Therefore, we aim to investigate the function
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