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V900462

Sigma-Aldrich

Cytosine

Vetec, reagent grade, 99%

Sinônimo(s):

4-Amino-2-hydroxypyrimidine, 4-Aminopyrimidin-2-(1H)-one

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About This Item

Fórmula empírica (Notação de Hill):
C4H5N3O
Número CAS:
Peso molecular:
111.10
Beilstein:
2637
Número CE:
Número MDL:
Código UNSPSC:
41106305
ID de substância PubChem:

grau

reagent grade

linha de produto

Vetec

Ensaio

99%

forma

powder

pf

>300 °C (lit.)

solubilidade

0.5 M HCl: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

cadeia de caracteres SMILES

NC1=NC(=O)NC=C1

InChI

1S/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8)

chave InChI

OPTASPLRGRRNAP-UHFFFAOYSA-N

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Informações legais

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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Irene M Kaplow et al.
Genome research, 25(6), 907-917 (2015-04-26)
DNA methylation is an epigenetic modification that plays a key role in gene regulation. Previous studies have investigated its genetic basis by mapping genetic variants that are associated with DNA methylation at specific sites, but these have been limited to
Rahul M Kohli et al.
Nature, 502(7472), 472-479 (2013-10-25)
DNA methylation has a profound impact on genome stability, transcription and development. Although enzymes that catalyse DNA methylation have been well characterized, those that are involved in methyl group removal have remained elusive, until recently. The transformative discovery that ten-eleven
Kian Peng Koh et al.
Current opinion in cell biology, 25(2), 152-161 (2013-03-19)
Changes in cellular phenotypes and identities are fundamentally regulated by epigenetic mechanisms including DNA methylation, post-translational histone modifications and chromatin remodeling. Recent genome-wide profiles of the mammalian DNA 'methylome' suggest that hotspots of dynamic DNA methylation changes during cell fate
Gitali Devi et al.
Nucleic acids research, 42(6), 4008-4018 (2014-01-16)
Peptide nucleic acids (PNAs) have been developed for applications in biotechnology and therapeutics. There is great potential in the development of chemically modified PNAs or other triplex-forming ligands that selectively bind to RNA duplexes, but not single-stranded regions, at near-physiological
Li Shen et al.
Current opinion in cell biology, 25(3), 289-296 (2013-03-19)
5-Methylcytosine (5mC) can be converted to 5-hydroxymethylcytosine (5hmC) in mammalian cells by the ten-eleven translocation (Tet) family of dioxygenases. While 5mC has been extensively studied, we have just started to understand the distribution and function of 5hmC in mammalian genomes.

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